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Trafficking Inside Cells
This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.
Regulators and Effectors of Small GTPases, Part E: GTPases Involved in Vesicular Traffic
Small GTPases play a key role in many aspects of contemporary cell biology: control of cell growth and differentiation; regulation of cell adhesion and cell movement; the organization of the actin cytoskeleton; and the regulation of intracellular vesicular transport.This volume and its companions (Volumes 255, 256, 257, and the forthcoming 325) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level.
Autophagy - From Molecular Mechanisms to Flux Control in Health and Disease
This textbook describes the autophagy pathway with all its key molecular mechanisms and its physiological functions from yeast to eukaryotes in a didactic and reader-friendly manner. It provides the most critical aspects that need to be understood to foster research and clinical translation in this area. Autophagy activity, mechanism and control in the context of cellular fate are central to this book, underpinned by human pathologies of priority. Further, key chapters describing major techniques required to assess autophagy activity, and highlighting starting points for the research of potential drug candidates and clinical translation, offer detailed insight into practice and application. The work represents a comprehensive study guide that allows undergraduate and postgraduate students in biology and biomedicine to rapidly engage with the most critical and recent aspects of autophagy in health and its control of disease. Written in a style that may be favourable for its use in the classroom, this book can also serve as a valuable source for teaching in the biomedical and medical sciences.
Mitophagy in Health and Disease
Mitophagy in Health and Disease: Mechanisms, Health Implications, and Therapeutic Opportunities is a complete reference to this key cellular process involved in homeostasis. The book addresses the machinery and mechanisms of mitophagy, including an overview of mito-biogenesis and dynamics and specific types of mitophagy. Other sections cover mitophagy across the human lifespan, from development to aging, discussing the interplay between inflammation and several conditions. The final part covers therapeutic opportunities presented by targeting mitophagy, including inducers and inhibitors, targeting strategies, and studies specific to cardioprotection and neurodegenerative diseases prevention. This is the ideal reference for cellular and molecular biologists needing a consistent and thorough overview of the subject, as well as research physicians in areas where mitochondria play a key role. - Covers biologic machinery and mechanisms involved with mitophagy - Explores changes in mitophagy across the human lifespan - Points out directions in targeting mitophagy with therapeutic interventions
Autophagy in Health and Disease
Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. It expands on the scope of the first edition by covering a wider range of cell types, developmental processes, and organ systems. The second edition is an international effort by investigators from 15 different countries whose many contributions are comprised in 28 chapters organized into six sections. The first section (Chapters 1-7) covers foundational concepts, including history, trajectory of the research field, mechanisms of autophagy, and autophagy regulation. The second section (Chapters 8-11) details developmental aspect...
Cumulative Subject Index
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Supplements index volumes 33, 75, 95, 120, 140, 175, 199, 229, 265, 285, and 320 Subject index Contributor index
The Journal of Cell Biology
No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-
