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In the recent years, the importance of infectious diseases in animals, with zoonotic diseases in particular, has dramatically increased with the presence of the COVID-19 pandemic, the emergence and/or re-emergence of African and Classical swine fever, vector borne diseases, avian influenza, moneypox and many more.
Besides causing direct damage associated with blood feeding and in some cases through the excretion of toxins with their saliva, the main relevance of ticks lies in the wide variety of pathogens that they can transmit, including viruses, bacteria, protozoa and helminths. Owing to socioeconomic and environmental changes, tick distribution is changing with incursions of ticks and tick-borne diseases occurring in different regions of the world when the widespread deployment of chemical acaricides and repellents has led to the selection of resistance in multiple populations of ticks. New approaches that are environmentally sustainable and that provide broad protection against current and future tick-borne pathogen (TBP) are thus urgently needed. Such development, however, requires improved understanding of factors resulting in vector competence and tick-host-pathogen interactions. This Research Topic provides an overview of known molecular tick-host-pathogen interactions for a number of TBPs and highlights how this knowledge can contribute to novel control and prevention strategies for tick-borne diseases.
The genus Campylobacter contains a number of important pathogens, both of humans and of livestock. C. jejuni and C. coli are responsible for the vast majority of human disease, causing hundreds of millions of infections worldwide each year. However, more recently, the roles of other Campylobacter species are increasingly becoming recognized as pathogens in their own right. Campylobacter-related infections are zoonoses, and are most commonly associated with consumption of contaminated poultry. However, as Campylobacter is carried asymptomatically in most avian species, acquisition of these bacteria from contaminated environmental sources may also play a significant role in infection. As with many bacteria, antibiotic resistance is widespread and increasing, leading to the US Centers for Disease Control and Prevention (CDC) to declare Campylobacter as a serious antibiotic resistance threat.
It is vital to understand ticks and tick-borne pathogens as well as their impact on humans. This book is intended for students in parasitology, biologists, parasitologists involved in molecular diagnostics of tick-borne diseases, practicing veterinarians, and for others who may require information on ticks and tick-borne diseases. Here we have put together a collection of chapters focused on different aspects of ticks and tick-borne diseases mainly to provide the reader with novel information in the field, but not the basic generalised information provided by many textbooks. This book includes topics such as high-throughput technologies in diagnosis, discovery of novel tick vaccines, identif...