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Membrane Structure and Mechanisms of Biological Energy Transduction
The problem of electron transfer phosphorylation was first formu lated in 1939 by Belitser and Tsibakova I who introduced the "P: 0" criterion and showed that this ratio is more than 1. The authors noted that such a high value of the phosphorylation coefficient suggests a fundamental difference in the mechanisms of A TP formation coupled with respiration, and glycolysis, since in the latter case, the amount of the ATP synthesized is equal to that of the substrate utilized. A lot of hypothetical schemes were put forward to explain the nature of coupling between electron transfer and phosphorylation, but none of them solved the problem. Only quite recently, one hypo thetical scheme of energy coupling, viz. Mitchell's chemiosmotic concept, 2.3 was supported by experimental data which allow us to prefer it to alternative possibilities. In this paper, I shall try to substantiate the statement that oxidation and phosphorylation can be coupled via a membrane potential as was postulated by Mitchell.
The Enzymes of Biological Membranes
For a long time membrane biochemistry was almost synonymous with the bio chemistry of electron transport and oxidative phosphorylation. Although the successful analysis of hormone receptors, active transport, and other membrane-linked metabolic systems displaced mitochondria from the focus of interest, the field continued to grow and its contributions to other areas of membrane biochemistry played a major role in their dramatic development. The eight chapters in this volume dealing with electron transport provide a concise, critical, and up-to-date picture of the problems and accomplishments of the field. In the remainder of the volume a brief summary of selected receptor functions is presented. The relative novelty of this field naturally limits the factual scope of developments and encourages speculation. Nevertheless these reviews accurately reflect both accomplishments and deficiencies and provide objective guidance for future development. Several receptor functions omitted from these discussions will form one of the later volumes currently in preparation.
The Molecular Biology of Membranes
On February 14, 1977, a symposium entitled "The Molecular Biology of Membranes" was held in New Orleans in honor of Professor David E. Green, whose many contributions in mitochondrial structure and metabolism have influenced and guided research in this important area of biochemistry for many years. The symposium was attended by many former and present-day colleagues, friends, and interested scientists. The contents of this volume represent papers that were delivered at the symposium and other contributions from individuals who have been associates of Professor Green. We wish to thank Plenum Press for their help in making the symposium and publication of this book possible. Sidney Fleischer Y...
Current Topics in Membranes and Transport
Current Topics in Membranes and Transport
Mosaic
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Progress in Nucleic Acid Research and Molecular Biology
Progress in Nucleic Acid Research and Molecular Biology
Mitochondria
Papers from a symposium held at the Instituto de biologia, Universidad Nacional Autonoma de Mexico, in June 1975.
Landmark Papers in Yeast Biology
The yeasts have been important experimental organisms for more than 50 years. This volume contains over 100 selected papers, in sections with introductions that describe the process of discovery and the context and significance of the research. The selections include early classics as well as recent advances in areas such as signal transduction, membrane trafficking, protein turnover, and genomics. This book is designed as a guide for a literature-based course.
Molecular Biology of the Cell
MBC online publishes papers that describe and interpret results of original research conserning the molecular aspects of cell structure and function.
