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Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Bloodâ¬"Brain Barrier
Despite substantial advances in developing treatments for the serious illnesses that affect people worldwide, there remains a tremendous unmet need in the treatment of complex neurologic diseases, including neuropsychiatric and neurodegenerative disorders. Chief among the challenges that have hindered the development of therapeutics for central nervous system (CNS) disorders is the bloodâ€"brain barrier (BBB). The Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop to explore the challenges associated with the BBB that have thus far stymied development of CNS drugs, examine new technologies that could address these challenges, and highlight potential opportunities for moving the field forward. This publication summarizes the presentations and discussions from the workshop.
Light, Molecules, Reaction and Health
Light, Molecules, Reaction and Health offers a comprehensive overview of health-related, light-based processes and systems, paying special attention to molecular photochemistry. Users of photochemical methods and concepts in pharmacology and biomedicine will find detailed information on the basic processes underlying the biological effects of natural and artificial light—from the primary absorption event occurring in an endogenous or exogenous molecule in a biological compartment, to the final pathological or beneficial outcome. By emphasizing novel methods, including nanostructured materials in therapy and diagnostics, this book allows readers to critically interpret existing data with a ...
Biolinguistics at the Cutting Edge
This book contains an updated discussion of the most relevant theoretical and methodological aspects, as well as the most important findings of biolinguistics. This field of linguistics is specifically concerned with the biological aspects of language. In doing so, the volume takes a timely look at the different angles of biolinguistics research, in particular considering its multidisciplinary, technical, theoretical, and applied approaches. The volume provides a comprehensive, in-depth, and state-of-the-art overview of the biolinguistics quest, bringing together the most outstanding contributions on exciting subfields such as language evolution, language acquisition, neuro- and psycholinguistics, or clinical linguistics.
NCRR Reporter
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The Future of the Brain
A leading scientist offers a unique perspective on the past, present, and future of neuroscience and the brain. 40 line illustrations.
Fluorescence-Guided Neurosurgery
The definitive textbook on state-of-the-art fluorescence-guided neurosurgery Advances in fluorescence-guided surgery (FGS) have resulted in a paradigm shift in neurosurgical approaches to neuro-oncological and cerebrovascular pathologies. Edited by two of the foremost authorities on the topic, Fluorescence-Guided Neurosurgery: Neuro-oncology and Cerebrovascular Applications encompasses the depth and breadth of this groundbreaking, still nascent technology. The book reflects significant contributions made by world renowned neurosurgeons Constantinos Hadjipanayis, Walter Stummer, and esteemed contributors on the growing uses of 5-aminolevulinic acid (5-ALA) and other FGS agents. The European M...
Neurosurgery Tricks of the Trade - Cranial
A collection of core procedures for the neurosurgeon… 2015 PROSE Award First Prize Winner! Neurosurgery Tricks of the Trade: Cranial presents core surgical procedures in a concise, highly didactic format, enabling surgeons to quickly grasp their essence from the bulleted text and superb illustrations that accompany them. Expert neurosurgeons specializing in the cranial region describe how they perform common procedures and offer surgical tips and pearls. Key Features: Distills a wealth of information in a concise, step-by-step format, making it easy for novice surgeons to review how procedures are performed Includes more than 150 surgical procedures for the cranial region, each accompanied...
Pediatric Epilepsy Surgery
The definitive reference for pediatric epilepsy surgery Written by internationally recognized authorities in pediatric epilepsy surgery, this cutting-edge book provides essential information about the preoperative assessment of and surgical approaches to the treatment of epilepsy in children. The book opens with an overview of pediatric epilepsy followed by four main sections detailing preoperative assessment, surgical approaches and techniques, outcomes, and recent promising advances. The authors present numerous approaches for managing temporal lobe epilepsy and extratemporal lobe epilepsy and guide clinicians through various surgical techniques for hemispherectomy, disconnection procedure...
The 21st-century Brain
This is a compelling and authoritative study of the brain - its past, present and future. The human brain is the most complex structure in the known universe. How it works, the relationship between mind and brain, is one of the most important of scientific questions. Researchers now claim to be able to explain the roots of human personality and behaviour and this new knowledge brings potential new powers; to cure mental illnesses, to control behaviour through tailor-made drugs, to develop human-machine hybrids. But just how seriously should we take these new threats and promises? In order to tackle these issues Steven Rose explores the evolutionary route by which brains emerged, from the origin of life to today's complex societies. He also investigates how brains develop from a single fertilised egg to the incredibly complex organ that each human possesses. Against this background he asks the challenging question: what does the future hold for the human brain?
The Economist
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