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Alzheimer's disease: new insights into biomechanisms and therapeutic target
With the prevalence of Alzheimer's disease on the rise among aging populations, it becomes crucial to acquire a comprehensive understanding of the underlying biomechanisms to enhance preventive measures for patients. Recent advances in the elucidation of basic biomechanisms such as the major role of the influential genetic factor TREM2 in the immunological basis of Alzheimer’s disease and the establishment of mechanobiology with relevance to Alzheimer’s diseases, hold promising translational value and potential for clinical applications. This research topic aims to elucidate the most recent progress in the field of basic and clinical research. Specifically, we will focus on areas such as the pathogenesis of Alzheimer's disease, neurodegenerative processes and early changes, perception and cognition deficits, immune regulation, as well as new therapeutic targets and innovative strategies. The topic editorial team is dedicated to advancing the field of Alzheimer's disease and creating a platform which future progress can be built upon.
MAGNUS PI & THE PATENT ACADEMY ENGINEERING THE BRAIN
On-Page Abstract (Publisher / Promotional Use) Engineering the Brain examines brain health and neurological decline through an engineering and systems-analysis framework, integrating global health data, regulatory history, and peer-reviewed research. The book evaluates how modern dietary patterns, food additive policies, and lifestyle factors contribute to chronic inflammation, metabolic dysfunction, and neurodegenerative disease risk. By contrasting current pharmaceutical management models with emerging evidence on neurogenesis and preventive nutrition, the work provides a structured, evidence-based overview of factors influencing long-term cognitive and neurological outcomes.
Adenosine Receptors
After a century of research, several lines of evidence now indicate that the ability of adenosine to directly control inflammatory cells has a major impact on the functions of the inflammatory and immune systems. Consequently, many promising therapeutic approaches are beginning to emerge that focus on the modulation of adenosine, including the deve
Biophysical Methods for Diagnosing Human Tissue Anomalies
Medical diagnosis of tissue anomalies, particularly cancer, is often limited by the constraints of current imaging technologies. This book introduces two approaches to address this issue: the imaging and the non-imaging methods. In the imaging category, the book unveils a pioneering technique based on radio tomosynthesis. Initially proven effective in detecting breast anomalies, this imaging method is now under evaluation for its potential in identifying brain anomalies. For non-imaging diagnostics, it delves into Fourier-transform infrared spectroscopy (FTIR), a technique known for its speed and reliability. The book demonstrates its successful application in diagnosing a range of cancers, including oral, uterine, ovarian, gastrointestinal, colorectal, and skin cancers. Furthermore, it explores its utility in predicting embryo quality and assessing pressure injuries. To augment these methods, the book employs machine learning algorithms, evaluating their efficacy in creating discriminative models for tissue anomalies.
New Scientist
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