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Regulation and Genetics
The time seems ripe for a critical compendum of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and numbering, has probably reached that stage at which relatively few new-truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high-resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 22 volumes, represents a commi...
Genetics of Influenza Viruses
With the advent of genetic engineering methods and improved biochemical tech niques, much has been learned about the replication of influenza viruses, their structure and their epidemiology. It appears that the time is ripe to review these efforts and to provide a molecular perspective of influenza virology. It is hoped that this book will stimulate our thinking, help us in designing new experiments, and possibly show avenues leading to the control of the diseases associated with influenza viruses. Peter Palese, New York, N. Y. August 1983 David W. Kingsbury, Memphis, Tenn. Contents List of Contributors. . . . . . . . . . . . . . . . . XV 1. The Evolution of Influenza Viral Genetics - A Pers...
Genetic Variation Among Influenza Viruses
Genetic Variation Among Influenza Viruses documents the proceedings of ICN-UCLA symposium held in Salt Lake City, Utah, 8-13 March 1981. The symposium brought together people from different disciplines working with the common objective of reducing the ravages of influenza and to expose them to the totality of the problem of influenza. The papers presented at the meeting included nearly all major aspects of influenza in which important advances are being made. Because of recombinant DNA technology and rapid DNA sequencing, a number of genes of influenza virus from a number of strains have been either completely or partially sequenced. Among these, the gene coding for hemagglutinin (HA) has be...
Comprehensive Virology
The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having only recently passed through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high-resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have so far been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 22 volumes, represent...
Virus Taxonomy
The practical need to partition the world of viruses into distinguishable, universally agreed upon entities is the ultimate justification for developing a virus classification system. Since 1971, the International Committee on Taxonomy of Viruses (ICTV) operating on behalf of the world community of virologists has taken on the task of developing a single, universal taxonomic scheme for all viruses infecting animals (vertebrate, invertebrates, and protozoa), plants (higher plants and algae), fungi, bacteria, and archaea. The current report builds on the accumulated taxonomic construction of the eight previous reports dating back to 1971 and records the proceedings of the Committee since publication of the last report in 2005. Representing the work of more than 500 virologists worldwide, this report is the authoritative reference for virus organization, distinction, and structure.
Advances in Genetics
Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field and make this an essential series of books for anyone in the genetics field.
Nonsegmented Negative Strand Viruses
Nonsegmented Negative Strand Viruses: Paramyxoviruses and Rhabdoviruses consists of papers presented at the Fifth International Symposium on Negative Strand Viruses, held at Hilton Head, S.C., on September 11-17, 1983.This book specifically contains papers on negative strand virus families with nonsegmented genomes, paramyxoviruses and rhabdoviruses. This reference shows the advances in the research of the two virus families, paramyxoviruses and rhabdoviruses. It also illuminates the various stages in the strategy of negative strand virus infections, including adsorption, penetration, mRNA transcription, translation, RNA replication, morphogenesis, and virus release. The biology of virus infection and host response are also addressed.
COVID-19 Pandemic – Philosophical Approaches
The paper begins with a retrospective of the debates on the origin of life: the virus or the cell? The virus needs a cell for replication, instead the cell is a more evolved form on the evolutionary scale of life. In addition, the study of viruses raises pressing conceptual and philosophical questions about their nature, their classification, and their place in the biological world. The subject of pandemics is approached starting from the existentialism of Albert Camus and Sartre, the replacement of the exclusion ritual with the disciplinary mechanism of Michel Foucault, and about the Gaia hypothesis, developed by James Lovelock and supported in the current pandemic by Bruno Latour. The soci...
RNA Viruses
RNA Viruses: A Practical Approach is wide ranging in scope, from emerging technology such as reverse genetics and retrovirus vectors, to money saving tips - how to make your own silica particles for high efficiency RNA extraction and liposomes for cell transfection! Chapter one covers the fundamentals of investigating RNA virus genome structure at a molecular level. Chapters two and three describe techniques for mutagenesis of RNA genomes and analysis of transcription. Chapter four deals with RNA virus-encoded proteinases, an important aspect of the control of RNA virus gene expression. Chapter five considers retrovirus oncogenesis and chapter six analysis of RNA virus quasispecies. Chapter seven describes systems for investigation of in vitro replication of positive-stranded viruses and chapter eight the packaging of RNA virus genomes. In addition to the technical aspects of reverse genetics and retrovirus vectors, both of the final two chapters also consider ethical aspects of these new technologies.
