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The Tenth International Conference on Intracellular Protein Catabolism was held in Tokyo Japan, October 30-November 3, 1994. under the auspices of the International Committee on Proteolysis (lCOP). ICOP meetings have been held biennially in the USA, Europe, and Japan in turn. The previous three ICOP meetings (7th to 9th) were held in Shimoda, Japan, in 1988. in WildbadKreuth, Germany, in 1990, and in Williamsburg. Virginia, in 1992. Previous meetings were held in resort areas, this was the first meeting held in a large city. Attendance has grown every year so that nearly 400 participants from 19 different countries attended the Tokyo meeting. At the meeting, novel and updated results on the ...
This conference and monograph were the result of many collective efforts. The whole concept was formulated one early Wednesday morning at our weekly research meeting at Children's Hospital in our division of urology. We have been most fortunate to have a close collaboration with Bob Levin, Ed Macarak, and Pam Howard who have helped steer the course of our division's growing interest in basic science. At our weekly meetings our laboratory fellow will summarize their current work. Other ongoing areas of investigation in our labs and elsewhere are discussed. We have always made an effort to try and understand what other groups are doing who are working in the area of bladder smooth muscle resea...
Development and Implications of Antimicrobial Resistance One of the most ominous trends in the field of antimicrobial chemotherapy over the past decade has been the increasing pace of development of antimicrobial resistance among microbial pathogens. The hypothesis that man can discover a magic bullet to always cure a particular infection has proved false. Physicians are now seeing and treating patients for which there are few therapeutic alternatives, and in some cases, none at all. Until recently there was little concern that physicians might be losing the war in our ability to compete with the evolving resistance patterns of microbial pathogens. Now the general public is very aware of the...
nd The 22 meeting of the International Society on Oxygen Transport to Tissue (LS. O. T. T. ) of which this volume is the scientific proceedings, was held in Istanbul, Turkey on August 22-26, 1994. It was a historical occasion in that it was almost 200 years to the day that one of the founding fathers of oxygen research, Antoine Lavoisier, on May 8, 1794 found his early demise at the hands of the guillotine. This spirit of history set the tone of the conference and in the opening lecture the contribution that this part of the world has given to the understanding of oxygen transport to tissue was highlighted. In particular, the contribution of Galen of Pergamon (129-200) was discussed who for ...
The contents of this book are the proceedings of the ACS symposium, "Fumonisins in Food," which was held April 4-6, 1995, at the American Chemical Society National Meeting in Anaheim, CA. This symposi"Qm, which was international in scope, brought together researchers from diverse backgrounds in academia, government, and industry. Thirty-three speakers discussed topics ranging from the analysis offumonisins to toxicology and regulatory aspects. The fumonisins became the spotlight of mycotoxin research in 1988, when re searchers at the South African Medical Research Council isolated and structurally charac terized the fumonisins. Since 1988, there has been an explosion in the numbers of papers dealing with fumonisin-related topics. The interest in the fumonisins has arisen for several reasons. First, fumonisins are found in measurable concentrations in corn grown throughout the world. Second, these compounds have been implicated as the causative agents in a variety of naturally occurring animal diseases. Finally, there is speCUlation that fumonisins may in part be responsible for the high incidence of esophageal cancer in regions of the world in which corn is the staple grain.
Support for the symposium came from the National Institute of Environmental Health Sciences, the U.S. Environmental. Protection Agency, Hoffmann-LaRoche, Inc., the International Society for the Study of Xenobiotics, the Drug Metabolism Section of International Union of Pharmacology, Rutgers, the State University of New Jersey, Thomas Jefferson University, the Medical University of South Carolina and the University of Maryland.The organizing committee for the conference included A.H. Conney (Hoffmann-LaRoche, Inc.), G.G. Gibson (University of Surrey), J.R. Gillettee (National Institutes of Health), D.J. Jollow (Medical University of South Carolina), J.J. Kocsis (Thomas Jefferson University), R.E. Menzer (University of Maryland), J.0. Nelson (University of Maryland), R. Snyder (Rutgers University) and C.M. Witmer (Rutgers University).
Gillette (USA), C.D. Klaassen (USA), J.J. Kocsis, (USA), D.B. Menzel (USA), M. Mercier (Belgium), R.A. Neal (USA), F. Oesch (BRD), S. Orrenius (Sweden), H. Remmer (BRD), M. Roberfroid (Belgium), H. Vainio (Finland) and C.M. Witmer (USA), acting 'as a committee under G.G. Gibson (UK), D.J. Jollow (USA), D.V. Parke (UK) and R. Snyder (USA), co-chairmen, THE SECOND INTERNATIONAL SYMPOSIUM ON BIOLOGICAL REACTIVE INTERMEDIATES was convened at the University of Surrey in the United Kingdom on July 14-17, 1980. This volume derives directly from the presentations at the symposium. The University of Surrey, which is located in Guildford, Surrey, provided a congenial atmosphere for this conference and...