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Epigenetic and Metabolic Regulators of Breast Carcinogenesis
Breast cancer is the most common tumor in females worldwide. Cancer epigenetics and metabolic reprogramming are known cancer hallmarks. Recent advances in the field of epigenetics include histone modification, DNA methylation, and non-coding RNAs. In contrast to genetic modifications, epigenetics refers to a set of dynamic alterations. By controlling the on and off states of oncogenes and tumor suppressor genes, as well as re-engineering the tumor microenvironment, epigenetics plays a crucial role in the initiation and progression of carcinogenesis. Additionally, the complex process of metabolic reprogramming is required for both malignant transformation and tumor development, including invasion and metastasis. Furthermore, reprogrammed metabolic activities have been utilized to diagnose, monitor, and treat cancer patients. In tumor tissues, metabolic heterogeneity was found to take a role in the adaptation to the microenvironment drastic changes resulting from current therapeutic modalities.
Applicative and Ecological Aspects of Mycorrhizal Symbioses
Mycorrhizal symbioses, a mutual association between plants and fungi plays a vital role in shaping and balancing the ecosystem of our planet. Approximately 80% of vascular plant species form mycorrhizal associations between their roots and soil borne fungi. Moreover, such association between plants and mycorrhizal fungi drastically affect the water and nutrient absorption by plant roots as well as provides protection against soil-borne pathogens. Hence, mycorrhizal symbioses might be advantageous for plants and our ecosystem under the drastically changing climate, which is threatening and distorting our ecosystem. Threats to our ecosystem should therefore encourage investigations and invento...
Advances in Computer Science and Information Engineering
CSIE2012 is an integrated conference concentrating its focus on Computer Science and Information Engineering . In the proceeding, you can learn much more knowledge about Computer Science and Information Engineering of researchers from all around the world. The main role of the proceeding is to be used as an exchange pillar for researchers who are working in the mentioned fields. In order to meet the high quality of Springer, AISC series, the organization committee has made their efforts to do the following things. Firstly, poor quality paper has been refused after reviewing course by anonymous referee experts. Secondly, periodically review meetings have been held around the reviewers about five times for exchanging reviewing suggestions. Finally, the conference organizers had several preliminary sessions before the conference. Through efforts of different people and departments, the conference will be successful and fruitful.
Copyright Law, Digital Content and the Internet in the Asia-Pacific
Copyright law, digital content and the Internet in the Asia-Pacific provides a unique insight into the key issues facing copyright law and digital content policy in a networked information world.
Advances in Guidance, Navigation and Control
This book features the latest theoretical results and techniques in the field of guidance, navigation, and control (GNC) of vehicles and aircraft. It covers a range of topics, including, but not limited to, intelligent computing communication and control; new methods of navigation, estimation, and tracking; control of multiple moving objects; manned and autonomous unmanned systems; guidance, navigation, and control of miniature aircraft; and sensor systems for guidance, navigation, and control. Presenting recent advances in the form of illustrations, tables, and text, it also provides detailed information of a number of the studies, to offer readers insights for their own research. In addition, the book addresses fundamental concepts and studies in the development of GNC, making it a valuable resource for both beginners and researchers wanting to further their understanding of guidance, navigation, and control.
Mechanical Components and Control Engineering III
Selected, peer reviewed papers from the 3rd Asian Pacific Conference on Mechanical Components and Control Engineering (MCCE 2014), September 20-21, 2014, Tianjin, China
Advances in Material Science, Mechanical Engineering and Manufacturing
Selected, peer reviewed papers from the 2013 3rd International Conference on Machinery, Materials Science and Engineering Applications (MMSE 2013), June 20-21, 2013, Wuhan, Hubei, China
