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Integrated Design and Manufacturing in Mechanical Engineering
This volume contains the selected papers of the first I.D.M.M.E. conference on 'Integrated Design and Manufacturing in Mechanical Engineering', held in Nantes from 15-17 April 1996. Its objective was to discuss the questions related to the definition of the optimal design and manufacturing processes and to their integration through coherent methodologies in adapted environments. The initiative of the Conference and the organization thereof, is mainly due to the efforts of the french PRIMECA group (Pool of Computer Resources for Mechanics) started eight years ago. We were able to attract the internationru community with the support of the International Institution for Production Engineering Research (C.I.R.P.). The conference brought together two hundred and fifty specialists from around the world. About ninety papers and twenty posters were presented covering three main topics : optimization and evaluation of the product design process, optimization and evaluation of the manufacturing systems and methodological aspects.
Preventive and Predictive Genetics: Towards Personalised Medicine
Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalized medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data. Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.
Product Modelling for Computer Integrated Design and Manufacture
This state-of-the-art text explores developments in geometric modeling, product modeling and their applications. In particular, it looks at the means by which product geometry emerges from the conceptual stages of design, and the use of geometric reasoning for applications downstream of design, including manufacture ands assembly. Much existing design research is either totally geometry based or totally non-geometric, and the interface between the two areas is of intense interest to industry, as well as being crucial for the successful development of integrated systems for design and manufacture. This interface is currently not well understood and the book makes a significant contribution towards its understanding. This book is essential reading for technical managers and research and development engineers.
Fractals in Engineering
Fractal analysis research is expanding into a variety of engineering domains. The strong potential of this work is now beginning to be seen in important applications in real industrial situations. Recent research progress has already led to new developments in domains such as signal processing and chemical engineering, and the major advances in fractal theory that underlie such developments are detailed here. New domains of applications are also presented, among them environmental science and rough surface analysis. Sections include multifractal analysis, iterated function systems, random processes, network traffic analysis, fractals and waves, image compression, and applications in physics. Fractals in Engineering emphasizes the connection between fractal analysis research and applications to industry. It is an important volume that illustrates the scientific and industrial value of this exciting field.
Handbook of ATPases
ATP-dependent active ion transport enables cells to regulate their pH value and to control their ion composition. The reverse process, transforming an ion imbalance into chemical energy, drives mitochondrial and chloroplast ATP synthesis. The mediators of these fundamental processes are ion-motive ATPases, highly conserved enzymes that play key roles in cell physiology from bacteria to man. As the first comprehensive overview of this important class of enzymes, this handbook summarizes recent knowledge about the molecular mechanism of ATPases, relating this information to the physiology and pathopyhsiology of ion transport, mitochondrial function, vesicle transport and lysosomal acidification. All important P-type, F-type and V-type ATPases are treated systematically, complemented by a special section on the cell biology and physiology of acidic compartments, and backed by an extensive bibliography and index. This premier reference source for physiologists, molecular biologists, biophysicists and clinical researchers contains contributions by the world's foremost ATPase research groups.
Alboran Sea - Ecosystems and Marine Resources
The Alboran Sea represents a regional Mediterranean space where North and South worlds merges, creating a geopolitical region where marine resources and maritime activities should be managed from a national and international perspectives. It is widely known, that currently the planet is suffering a global change, and it is also affecting the Alboran Sea, its ecosystems and populations. An important first step to update a paramount vision on this region is to understand the climatic, geologic and oceanographic, including biochemical cycles, process which shapes the rich geodiversity, biodiversity, the productivity, and the sustainable use of the marine resources from Alboran Sea. The fisherie...
Deepwater Sedimentary Systems
Deepwater Sedimentary Systems: Science, Discovery and Applications helps readers identify, understand and interpret deepwater sedimentary systems at various scales – both onshore and offshore. This book describes the best practices in the integration of geology, geophysics, engineering, technology and economics used to inform smart business decisions in these diverse environments. It draws on technical results gained from deepwater exploration and production drilling campaigns and global field analog studies. With the multi-decadal resilience of deepwater exploration and production and the nature of its inherent uncertainty, this book serves as the essential reference for companies, consul...
