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This authoritative volume provides a contemporary view on the latest research in molecules with optimal drug-like properties. It is a valuable source to access current best practices as well as new research techniques and strategies. Written by leading scientists in their fields, the text consists of fourteen chapters with an underlying theme of early collaborative opportunities between pharmaceutical and discovery sciences. The book explores the practical realities of performing physical pharmaceutical and biopharmaceutical research in the context of drug discovery with short timelines and low compound availability. Chapters cover strategies and tactics to enable discovery as well as predic...
This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characteriz...
This book begins with a brief background on greenhouse gases sources and sinks and continues with a discussion in different sectors including forest fluxes to human health and modeling techniques to policy measures. The chapters explore in detail about the GHG emission budgets, mitigation strategies, technical advancement and input-output analysis. Greenhouse gases (GHGs) occur naturally in our atmosphere and are essential to the survival of most of the organisms on the planet earth. GHGs such as such as carbon dioxide, methane, nitrous oxide, and ozone etc. play a major role in balancing the radiative budget, by absorbing or emitting some of the infrared rays reflecting from the earth’s s...
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
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A weekly record of scientific progress.
Jan. 2003- : "7 directories in 1: section 1: alphabetical section; section 2: business section; section 3: telephone number section; section 4: street guide; section 5: map section; section 6: movers & shakers; section 7: demographic summary."
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