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Neonatal and Early Onset Diabetes Mellitus
This comprehensive volume collects contributions by leading experts on neonatal diabetes. It provides the reader with the most up-to-date information about all the progresses that have been made and that have led to the clarification of the pathogenesis of all the forms of diabetes. From pathogenesis to novelty in therapy, the book will cover all aspects of the diagnosis and treatment also discussing rare forms of early onset diabetes, insulin therapy, pump therapy and technologies, acute and chronic complications. The volume is enhanced by videos showing the impact of treatments on movement difficulties, psychomotor development, and muscle tone. Slide decks with key messages are also available for download and usage during congresses and lessons. This book will be of benefit to pediatricians, endocrinologists, neonatologists and all physicians who deal with neonates affected by this disease
Glucose Metabolism Derangements in Pediatric Age
This book addresses the difficult field of pediatric glycometabolic disorders, which have often been considered the exclusive field of specialists in the sector. However, if all the intricate subjects of long-term treatment of type 1 diabetes are certainly a specialist field, the diagnosis of type 1 diabetes or its distinction from other forms of diabetes cannot be considered fields of strict specialization. Indeed, hypoglycemia, metabolic syndrome due to obesity, and drug-induced hyperglycemia are not specialized fields. Instead, we often see the clinician withdrawing from these pathologies. This book provides the trainee pediatric specialist with robust preliminary knowledge of the field.
Tumor Hypoxia: Impact in Tumorigenesis, Diagnosis, Prognosis and Therapeutics
Hypoxic regions have been identified within tumors and its presence has been linked to malignant progression, metastasis, resistance to therapy, and poor clinical outcomes following treatment. Acute and chronic hypoxia are integral components of tumor microenvironment and conduce to metabolic adaptations of tumor cells leading to genetic instability, intratumor heterogeneity and malignant progression. On the success of our fight against cancer, the continued adaptability of tumors to their microenvironmental stresses, such as hypoxia, must be considered. Tumor cells are endowed with a very high plasticity and capacity to adapt. It is our challenge to find populations and conditions of the tumor microenvironment germane for target success. Interdisciplinary work will be the key for achievement of these goals. This e-book is a compendium of original reports and review articles contributed by world-class experts in the field of tumor hypoxia. This material will be useful to foster discussion and increase understanding of the involvement of hypoxia in tumorigenesis, biomarker development, and therapeutics.
Glucokinase and Glycemic Diseases
The glucose-phosphorylating enzyme glucokinase (also known as hexokinase IV) plays a preeminent role as a glucose sensor and regulatory metabolic enzyme. The implications of this central position of glucokinase for the understanding and treatment of diabetes mellitus are far reaching. This book addresses the molecular and human genetic, as well as the physiological-chemical and pharmacological aspects of the role glucokinase plays in glucose homeostasis and diseases of glucose metabolism, and how the enzyme serves as the drug target for the treatment of diabetes mellitus. The collection of assays by a team of internationally renowned authors includes basic science chapters dealing with the e...
The Racing Calendar
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Hypoglycemia
Abstract: A reference book for clinical pathologists, health care professionals and researchers presents full text of 30 technical papers and summaries of 15 poster papers presented at an international symposium dealing the clarification of hypoglycemia and its clinical manifestations. The papers are grouped among 4 themes, viz.: aspects of "functional" hypoglycemia; immunological aspects; neurological interrelations with hypoglycemia; and forensic aspects (e.g., alcohol, drugs, criminality). Tabular data, illustrations, and literature citations are presented throughout the text.
The Ovary
Hardbound. Despite all the advancements and current understanding of the endocrine processes that regulate the female reproductive system, deranged menstrual and ovulatory function has remained a serious and unresolved problem for many women.This volume is the second based on a series of Conferences in Reproductive Medicine sponsored by Ferring Arzneimittel GmbH and covers new research findings and timely updates on ovarian physiology and pathophysiology, as well as on therapeutic options available for the management of PCO. It will be of value to investigators and clinicians who are active in the area of Reproductive Endocrinlogy.
