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Pearls of Glaucoma Management
If you have ever uttered the commonly expressed lament, “Glaucoma is so confusing!” then this text is for you. You will no longer be bewildered. Why practitioners may be confused about how to be of help to patients with glaucoma – in its many incarnations and reincarnations – is easily understood. The issue seems to be overwhelming when one considers that the already massive popu- tion of those with glaucoma is increasing rapidly as the world’s population increases and ages. During the past 50 years the fundamental defnition of glaucoma has changed almost 180°, and the indications for treatment have become more variable and c- troversial, some advising early therapy and others strongly cautioning against such an approach: Various diagnostic tests have come and gone and are interpreted in such different ways that there seems to be no consensus; surgical techniques come in and out of fashion in perplexing ways. There seems to be a constantly shifting, sandy foundation on which are built unsteady schools of ever-varying advice. Why prac- tioners, patients, and the public are often bewildered is understandable.
Pharmacotherapeutics for Bone and Soft Tissue Tumours
Accounting for approximately 1% of all new cancers diagnosed globally, bone and soft tissue sarcomas are rare malignancies. Their high heterogeneity with more than a hundred subtypes has further undermined the development of robust, evidence-based treatment strategies, and our therapeutic approach is hardly patient-specific or widely standardized. Therefore, generating the appropriate evidence of high quality for the diagnosis and treatment is challenging. Although surgery is the mainstay treatment in most cases, radiotherapy and chemotherapy are included in the current clinical practice of bone and soft tissue sarcomas management. In the last decades, molecular targeting agents have shown favourable performance in some specific types of these sarcomas and even in some aggressive benign tumours. The purpose of this research topic is to provide a platform for researchers who work on bone and soft tissue tumours to explore more effective pharmacotherapeutics with an emphasis on molecular targeting agents.
Representations of Lethal Gender-Based Violence in Italy Between Journalism and Literature
This book discusses femicide in Italy, and the cultural conversations that have resulted from feminist discourse on lethal violence against women entering the mainstream, by analyzing journalistic inquiries and literary works produced after 2012. In a global and national context where activism’s goals are mainly discursive this study deepens our understanding of the role played by written narratives in the critique of a public interest matter such as gender-based violence. The first part of the book is dedicated to the analysis of three journalistic inquiries published in book format that focus on one or more cases of femicide that happened on the Italian peninsula. The second section draw...
A Criminal Hero
In the spring of 1757, the Augustinian friar Leopoldo di San Pasquale was tried in Naples by the hierarchies of his own religious order on charges of financial fraud, heresy, and sexual immorality. He responded by accusing the heads of the convent of subjecting him to a series of inhuman cruelties, claiming to have been "buried alive". While waiting for a final judgment (it was pronounced seven years later, in 1764), the trial of Leopoldo di San Pasquale became a cultural phenomenon unlike any witnessed before in Naples. Cumulatively, reactions to the trial, both during and after it, broke the boundaries separating chronicle and literary fiction, engaged people’s faculties of reason and em...
New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System – Part B
New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System - Part B is the latest volume from Progress in Brain Research focusing on new trends in basic and clinical research of glaucoma. This established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields. - This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields
Medici ~ Ascendancy
Florence, 1429 Giovanni de' Medici is dead. A lifetime of shrewd investment, strategic alliance and sly manipulation saw Giovanni climb from mere money-lender to the top echelon of Florentine society. But success has left a slew of bitter enemies in his wake – and there are whispers his untimely demise wasn't accidental. Florence is a nest of vipers, and with the Medici family's wealth in the hands of Giovanni's untested sons, Cosimo and Lorenzo, there are those who feel that now is the time to strike, to destroy the upstarts and seize their holdings. First in an award-winning, bestselling quartet charting ten generations of rise to power. Praise for Matteo Strukul: 'Strukul has a brilliant style and a rare imagination' TIM WILLOCKS 'One of the most important new voices in Italian crime fiction' JOE R. LANSDALE
Medici ~ Legacy
The third instalment in a prize-winning series charting the rise of the House of Medici as they become Masters of Florence and progenitors of the Renaissance. Fontainebleau, 1536. Francis II, Dauphin and heir to the French throne, is dead. Poisoned. And the royal court believe Catherine de' Medici to be the murderer. Catherine's husband Henry will now be the next King of France – and the Medici are known to stop at nothing in the pursuit of power. But not yet queen and without an heir of her own, seventeen-year-old Catherine cannot be sure of securing her family's legacy. To ensure the conception of an heir, she will need to seek help from an unexpected ally: Nostradamus, the reclusive ast...
Il Mulino
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Cell Transplantation
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