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The Gene Card
As former secretary of the Department of Health and Human Services, Dr. Peter Kelly knows that the new president-elect, Joseph Thorn, will continue the previous administration's disastrous healthcare reform. He's seen firsthand the terrible price the reform has cost families. His own son has become a victim of the new "affordable and practical" healthcare system. But even worse, Kelly realizes that it is his own original proposal that landed America in this tragic mess. Ten years ago, Kelly only wanted to reduce suffering and move much-needed funds to where they would do the most good for patients instead of increasing the bottom lines of politicians and conglomerate healthcare industries. I...
Mitochondrial Disease Genes Compendium
The field of Mitochondrial Medicine has been dominated by symptom constellation-based diagnostic categorization since the first clinical syndrome was described three decades ago. Now, as rapidly expanding knowledge has revealed that mitochondrial diseases may result from several hundred distinct gene disorders with extensive clinical and mutation heterogeneity, the most useful guide for clinical care and research embraces a gene-centric approach to each individual's disorder. Together with international colleagues, Dr. Marni Falk has developed the Mitochondrial Disease Sequence Data Resource (MSeqDR), an online, community curated, centralized data resource of mitochondrial disease data from ...
Cells and Biomaterials in Regenerative Medicine
This book serves as a good starting point for anyone interested in the application of tissue engineering. It offers a colorful mix of topics, which explain the obstacles and possible solutions for TE applications. The first part covers the use of adult stem cells and their applications. The following chapters offer an insight into the development of a tailored biomaterial for organ replacement and highlight the importance of cell-biomaterial interaction. In summary, this book offers insights into a wide variety of cells, biomaterials, interfaces and applications of the next generation biotechnology, which is tissue engineering.
Machine Learning for Multimodal Healthcare Data
This book constitutes the proceedings of the First International Workshop on Machine Learning for Multimodal Healthcare Date, ML4MHD 2023, held in Honolulu, Hawaii, USA, in July 2023. The 18 full papers presented were carefully reviewed and selected from 30 submissions. The workshop's primary objective was to bring together experts from diverse fields such as medicine, pathology, biology, and machine learning. With the aim to present novel methods and solutions that address healthcare challenges, especially those that arise from the complexity and heterogeneity of patient data.
Network Pharmacology
This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid atten...
Quality Issues in Clinical Genetic Services
Initially genetic disorders were all considered as rare diseases. At present, in the mid of 2009, the OMIM catalogue contains information on more than 12 000 entries of which about 2500 are available for clinical testing based on the identification of the responsible gene defect. However, altogether it has been estimated that about 8 percent of a population in the economically developed countries will during their lifetime suffer from a disease mainly as the result of their genetic constitution. Adding to that, it is estimated that all diseases have a genetic component, which will determine who will be at a higher than average risk for a certain disorder. Further it is postulated that in the...
Big Data Analytics for Intelligent Healthcare Management
Big Data Analytics for Intelligent Healthcare Management covers both the theory and application of hardware platforms and architectures, the development of software methods, techniques and tools, applications and governance, and adoption strategies for the use of big data in healthcare and clinical research. The book provides the latest research findings on the use of big data analytics with statistical and machine learning techniques that analyze huge amounts of real-time healthcare data. - Examines the methodology and requirements for development of big data architecture, big data modeling, big data as a service, big data analytics, and more - Discusses big data applications for intelligent healthcare management, such as revenue management and pricing, predictive analytics/forecasting, big data integration for medical data, algorithms and techniques, etc. - Covers the development of big data tools, such as data, web and text mining, data mining, optimization, machine learning, cloud in big data with Hadoop, big data in IoT, and more
Lange Microbiology and Infectious Diseases Flash Cards, Second Edition
The fun, fast, portable way to review microbiology and infectious diseases Market: Medical Students (18,750); Physician Assistant Students (3,000); Nurse Practitioner Programs Great review tool for the boards and course exams Every card includes a board-style clinical vignette Format allows students to compare and contrast diseases 220 High Yield Cards Kenneth D. Somers, Ph.D. Eastern Virginia Medical School, Norfolk, VA, and Stephen Morse, Center for Infectious Diseases, Center of Disease Control, Atlanta GA
Gene Mapping
This timely work brings together a group of the nation's leading experts in genetics, medicine, history of science, health, law, philosophy of science, and medical ethics to assess the current state of modern human genetics, and to begin to chart the legal and ethical guidelines needed to prevent the misuse of human genetics from leading to the abuse of human beings. The six sections of the book, read together, map the social policy con tours of modern human genetics. The first part describes the science of the Human Genome Project. The second addresses specific social policy implications, including the relevance of recombinant DNA history, the eugenics legacy, military applications, and issues of race and class in the context of genetic discrimination. Broader philosophical issues, including reductionism and determinism, the concept of disease, and using germline gene therapy to "improve" human beings are discussed in the third part.
