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High-throughput genomics has been increasingly generating the massive amount of genome-wide data. With proper modeling methodologies, we can expect to archive a more comprehensive understanding of the regulatory mechanisms of biological systems. This work presents integrative approaches for the modeling and analysis of gene regulatory systems. In mammals, gene expression regulation is combinatorial in nature, with diverse roles of regulators on target genes. Microarrays (such as Exon Arrays) and RNA-Seq can be used to quantify the whole spectrum of RNA transcripts. ChIP-Seq is being used for the identification of transcription factor (TF) binding sites and histone modification marks. RNA int...
This publication of a symposium held on 24 th and 25 th of June 1988 in Munich th is dedicated to Nepomuk Zollner on the occasion of his 65 birthday, expressing the best wishes of the authors. Nepomuk Zollner was born in the northern part of Bavaria. While a medical student in Munich he was called up to military duty in the last year of World War II. After achieving excellent results on his examinations he served as a physician in several hospitals in Munich and soon became interested in inborn errors of metabolism. In order to receive the best education possible at that time he joined the group of S. J. Thannhauser, the famous German emigrant, in Boston where he worked from 1951 to 1953. Th...
'Echoes' of Robert E. Lee High School is an anthology about the first decade of Robert E. Lee High School in Montgomery, Alabama, written and compiled by persons who supplemented their unique personal experiences at the school with research on the same. The "echoes" of the title refers to how life experiences reverberate back to us. Thus, from the beginning, its editors and writers thought of this little book of big memories and lessons of life as a compendium of the strong, positive echoes they recall from Lee and the few negative ones they cannot forget, which seem still to be informing and inspiring the lives of the school's graduates. The audience for Echoes is, of course, all past Lee High alumni, faculty, and staff and all present and prospective Lee students, faculty, and staff, along with any who support or have supported them and/or the school, and any others with sufficient connections to Lee or Lee people to enjoy reading others' recollections of their time there. The book might also be useful to anyone with a general interest in public secondary education in Montgomery County.
Long before Trussville became the commercial hub of northeastern Jefferson County, settlers fell in love with the area's fertile land and proximity to Alabama's longest free-flowing river, the Cahaba. In the late 1930s, a New Deal initiative known as the Cahaba Project established nearly three hundred new homes in the city, a community that became a historic treasure. The Trussville Academy opened its doors in 1869 and is the area's first educational institution. Camp Gertrude Coleman, which opened in 1925, is the third-longest-operating Girl Scouts camp in the nation, remaining open even during the Great Depression and World War II. Join author Gary Lloyd as he recounts the people and events that make Trussville one of the most desirable places to live in Alabama.
The editors of this book have brought together contributions from leaders in the application of "in situ" hybridization and guide the reader through the various options and variations of the technique.
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Richard Foster (b.ca. 1619/1620), a descendant of King Henry I of England, immigrated in 1635 from England to Elizabeth City County, Virginia, and married Sussan Garnett. They moved to land in Lower Norfolk County, Virginia in 1653, and in 1655 to land in Gloucester County, Virginia. Descendants and relatives lived in Virginia, Kentucky, Illinois, Missouri, Kansas, Texas, Arizona, California and elsewhere.