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Genes exist predominantly as families with related structures and functions, particularly within eucaryotic organisms. The isozyme concept was first introduced by Markert and MØller in 1959, and has formed the basis of large numbers of scientific investigations and conferences on gene families since that time. This volume is based on presentations made by invited Plenary and Symposia speakers at the Eighth International Congress on Isozymes on the topic of Gene Families: Structure, Function, Genetics and Evolution. The major themes for the Congress were in the following areas: molecular evolution; population genetics; enzymology; Australian fauna; biomedical aspects; molecular genetics; cellular compartmentation; gene regulation; and developmental genetics.
Progress in Nucleic Acid Research and Molecular Biology
Volume 39: Molybdenum and Tungsten: Their Roles in Biological Processes is devoted soley to the vital research area on molybdenum and tungsten and their role in biology. It offers a comprehensive and timely account of this fascinating topic by 40 distinguished international authorities. Topics include: transport, homeostasis, regulation and binding of molybdate and tungstate to proteins, crystallographic characterization, coordination of complexes, and biosynthesis.
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The last few years have seen major advances in our understanding of the molecular and genetic events associated with alcohol abuse. The advent of recombinant DNA technology has allowed the structure of the genes and proteins of alcohol metabolism to be identified, and this work has formed the basis for genetic studies of factors that influence drinking behavior and alcoholism. This book provides an introduction for the non-specialist reader to recent developments concerning the molecular pathology of alcohol-related disease. It gives substance to the view that alcoholism is an organic disorder that stems from the specific interaction of alcohol and its metabolites with cellular components. Particular attention is paid to the molecular biology of the enzymes of alcohol metabolism.
The first two volumes of the "Handbook of Metalloproteins", published in 2001, focused on a number of metals, including iron, nickel, manganese, cobalt, copper and vanadium. Now we are delighted to present volume three which extends the wealth of knowledge and focuses on proteins found in the redox-inactive ions of zinc and calcium. (Midwest).