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Multiple Stressors: A Challenge for the Future
Ecotoxiclogical risk from multiple stressors covers any situation where org- isms are exposed to a combination of environmental stressors. These include physical and chemical pollutants as well as other stressors such as parasites and environmental impact (e. g. , climate change or habitat loss). The combi- tion of stressors can result in increased risk to organisms (either additive or synergistic effects) or decreased effects (protective or antagonistic effects). The multiple stressor challenge is an international, multi-disciplinary problem requiring an international, multi-disciplinary approach. The c- rent approach to multiple stressors is to examine one stressor at a time and assume add...
Environmental Toxicology
This sixth volume in this established series deals with the biochemical responses of fish to different environmental/ecological factors. Environmental Toxicology captures vital issues affecting the responses of fish to the chemical surroundings of their environment. Chapters included in this volume identify the systems found in fish to deal with xenobiotics, hormonal interactions initiated in the presence of these chemicals, the unique mechanisms used by fish to adjust to the present chemicals, and the new and evolving mixtures of chemicals in their environment. Also included, is a crucial review of the new methods being applied in fish systems to understand the effects of xenobiotics to fish fitness - a key theme in environmental health and critical to the future of fish populations.* Entirely new topic discussion and most recent volume in the acclaimed series* Includes chapters detailed on a cellular level * Introduces discussion of pharmaceutical effects on fish
Reproductive Toxicology
Numerous reports demonstrate that the reproductive system could be affected by multiple potential toxicological agents. The volume includes different aspects of the development of new approaches to in vitro testing using sperm cells and systems involved on reproduction in mammals. Comparative analysis of in vivo and in vitro methods has been included to take steps towards the further development of and applications of new systems for germline toxicology.
Risk-Informed Management of European River Basins
The growing impacts of economic activities and climate change on the conditions of rivers throughout the world, require a new, integrated approach towards river basin management, an approach that can also cope with an uncertain future. In this volume, leading European scientists and representatives of major stakeholder groups present risk-informed management as this new approach, as developed in the European Commission-funded project RISKBASE. It aims to improve the ecological quality of river basins and thus to sustain the goods and services they provide for the benefit of society. Risk-informed management involves the integrated application of three key-principles: · Being well informed · Managing adaptively · Pursuing a participatory approach The authors explain and underpin these principles in detail, offer inspiring examples from practice and connect them to the implementation of the European Water Framework Directive (WFD). This book is intended for scientists, consultants and practitioners concerned about river basins, world-wide, as well as the drafters and implementers of the WFD River Basin Management Plans.
The Hepatocyte Review
It is thirty years since the technique of high-yield preparation of isolated hepatocytes, by collagenase perfusion of the liver, was published. The original method described by Berry and Friend has undergone many minor modifications by other workers, and the two-step procedure introduced by Seglen in 1976 has become the most frequent way to prepare hepatocyte suspensions. An important development introduced by Bissell in 1973 was the use of the cells as the first step in monolayer culture. The availability of the isolated hepatocyte preparation as cells in suspension or culture has undoubtedly facilitated research on the liver. This was emphasised in our book, published (with Dr. Greg Barrit...
Target Organ Toxicity in Marine and Freshwater Teleosts
Addressing the numerous gaps in current information, Target Organ Toxicology in Marine and Freshwater Teleosts is an essential resource for researchers and professionals in aquatic toxicology and environmental risk assessment. All the chapters are written by researchers who are internationally recognised for their work in mechanistic aspects of aquatic toxicology. Each chapter focuses on a specific target organ or physiological system and describes how various agents disrupt the normal physiological system and processes. This volume is devoted to specific organs with coverage of the gill, kidney, skin, liver and gut. The companion volume, Systems, provides coverage of toxic effects in the central nervous, immune, neurobehavioural and reproductive systems as well as describing general mechanisms of toxicity.
Ecotoxicology
A fresh and comprehensive overview of ecotoxicology today This book provides comprehensive single-source coverage of the entire field of ecotoxicology, from the ecological basics to the effects of chemicals on the environment and the latest test strategies. Contributions by leading figures in ecotoxicology from around the world reflect the broad scope of current thinking and research, making this volume essential reading for informed professionals and students. Areas covered include: * Ecosystem sensitivity, principles for analysis, and other fundamentals * Fate, distribution, and speciation of chemicals in the environment * Bioaccumulation and effects of chemicals * Ecotoxicological test systems * Concepts of ecological risk assessment Incorporating numerous examples and case studies, this cutting-edge reference is an invaluable resource for those working in environmental toxicology, chemistry, ecology, medicine, engineering, and other related disciplines.
