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Dictionary
No detailed description available for "Dictionary".
Nicene and Post-Nicene Fathers
"The Council of Nicaea in 325 AD marked the beginning of a new era in Christianity. For the first time, doctrines were organized into a single creed. The Nicene and Post-Nicene Fathers did most of their writing during and after this important event in Church history. Unlike the previous era of Christian writing, the Nicene and Post-Nicene era is dominated by a few very important and prolific writers. In Volume VII of the 14-volume collected writings of the Nicenes and Post-Nicenes (first published between 1886 and 1889), readers will discover Saint Augustines commentaries on the writings of John and his first writings as a newly converted Christian. In the Soliloquies, Augustine reasons through his conversion, trying to justify his new faith; these are intensely personal journeys toward truth, the product of a thoughtful soul seeking comfort and reassurance. Spiritual seekers wavering in their faith may find both sections of this book helpful in exploring their beliefs."
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Protein Tyrosine Kinases
Leading researchers, from the Novartis group that pioneered Gleevec/GlivecTM and around the world, comprehensively survey the state of the art in the drug discovery processes (bio- and chemoinformatics, structural biology, profiling, generation of resistance, etc.) aimed at generating PTK inhibitors for the treatment of various diseases, including cancer. Highlights include a discussion of the rationale and the progress made towards generating "selective" low molecular-weight kinase inhibitors; an analysis of the normal function, role in disease, and application of platelet-derived growth factor antagonists; and a summary of the factors involved in successful structure-based drug design. Additional chapters address the advantages and disadvantages of in vivo preclinical models for testing protein kinase inhibitors with antitumor activity and the utility of different methods in the drug discovery and development process for determining "on-target" vs "off-target" effects of kinase inhibitors.
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