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This Research Topic is part of a series with, "Bioinformatics Analysis of Omics Data for Biomarker Identification in Clinical Research - Volume I" (https://www.frontiersin.org/research-topics/13816/bioinformatics-analysis-of-omics-data-for-biomarker-identification-in-clinical-research) The advances and the decreasing cost of omics data enable profiling of disease molecular features at different levels, including bulk tissues, animal models, and single cells. Large volumes of omics data enhance the ability to search for information for preclinical study and provide the opportunity to leverage them to understand disease mechanisms, identify molecular targets for therapy, and detect biomarkers ...
Xiaorong Han explores how Chinese intellectuals envisioned the peasantry and its role in changing society during the first half of the twentieth century. Politically motivated intellectuals, both Communist and non-Communist, believed that rural peasants and their villages would be at the heart of change during this long period of national crisis. Nevertheless, intellectuals saw themselves as the true shapers of change who would transform and use the peasantry. Han uses intellectuals' writings to provide a comprehensive look at their views of the peasantry. He shows how intellectuals with varying politics created images of the peasant—a supposed contemporary image and an ideal image of the peasant transformed for political ends, how intellectuals theorized on the nature of Chinese rural life, and how intellectuals conceived their own relationships with peasants.
This is a unique and groundbreaking collection of questions and answers coming from higher education institutions on diverse fields and across a wide spectrum of countries and cultures. It creates routes for further innovation, collaboration amidst the Sciences (both Natural and Social) and the Humanities and the private and the public sectors of society. The chapters speak across socio-cultural concerns, education, welfare and artistic sectors under the common desire for direct responses in more effective ways by means of interaction across societal structures.
This book presents the proceedings of the 6th International Conference on Frontier Computing, held in Kuala Lumpur, Malaysia on July 3–6, 2018, and provides comprehensive coverage of the latest advances and trends in information technology, science and engineering. It addresses a number of broad themes, including communication networks, business intelligence and knowledge management, web intelligence, and related fields that inspire the development of information technology. The contributions cover a wide range of topics: database and data mining, networking and communications, web and internet of things, embedded systems, soft computing, social network analysis, security and privacy, optical communication, and ubiquitous/pervasive computing. Many of the papers outline promising future research directions. The book is a valuable resource for students, researchers and professionals, and also offers a useful reference guide for newcomers to the field.
There is a growing evidence that cross-reactive immunity from common human coronaviruses (hCoVs) can shape the immunological response to SARS-CoV-2. Cross-reactive T cells appear to play a protective role against disease but there is no consensus on the role of cross-reactive antibodies, with some authors reporting protective effects/mechanisms and other authors reporting evidence of negative interference due to the generation of low-affinity antibodies in the context of an “original antigenic sin”. Reports of association of pre-existing immunity to hCoVs and milder clinical manifestations of COVID-19 conflict with other reports showing in COVID-19 patients a strong back-boosting of anti...
Money? I have over a hundred billion yuan. Beautiful women? I live every day with my arms around my body. Status? Wait a minute, I'll talk to the boss about this project first. Ding Ergou, whose family had fallen, climbed up from the ground. Step by step, he stepped onto the peak, leading a life surrounded by many beauties!
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The Ming period of Chinese history is often depicted as one of cultural aridity, political despotism, and social stasis. Recent studies have shown that the arts continued to flourish, government remained effective, people enjoyed considerable mobility, and China served as a center of the global economy. This study goes further to argue that China’s perennial quest for cultural centrality resulted in periodic political changes that permitted the Chinese people to retain control over social and economic developments. The study focuses on two and a half million people in three prefectures of northeast Henan, the central province in the heart of the "central plain”--a common synecdoche for C...