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Epitranscriptomics: The Novel RNA Frontier
Following the formulation of the central dogma of molecular biology and the later discovery of classes of non-coding RNAs, the primary focus of Genetics was essentially on variation of DNA aiming at elucidating biological pathways perturbed in diseases. Recently, extensive attention has shifted towards the study of posttranscriptional RNA modifications occurring in both protein-coding as well as non-coding RNAs, revealing a novel and finer layer of complexity in gene regulation. This, in turn, has led to the birth of the novel field of ‘Epitranscriptomics’. The recent increase of applications of high-throughput sequencing technology (HTS) has allowed the unprecedented opportunity to iden...
Plant Stress – A Threat to Food Security
The adverse effects of abiotic stresses on plants, including crops, is a growing and pressing problem across the globe. The topic is particularly timely nowadays due to climate change and associated weather extremes such as heat waves, drought, flooding and heavy precipitation. In addition, the yield and quality of crop plants is affected by general global change including man-made factors such as novel xenobiotics or change of land use. Fortunately, plants can detect unfavorable conditions and adjust to environmental changes. The cellular and developmental plasticity of plants enables them to adapt to changing conditions and leads to the improvement of their productivity under sub-optimal environmental conditions. Gaining better insight into plant responses to abiotic stresses is crucial to develop methods for enhanced crop production and elaborate strategies designed to improve global food security.
