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Considerable progress has been made in our healthcare system, in particular with respect to sensitive diagnostic tools, reagents and very effective and precise drugs. On the other hand, high-throughput screening technology can screen vast numbers of compounds against an array of targets in a very short time, and leads thus - tained can be further explored. In developing countries, the exploding population exerts pressure not only on natural resources but also on the human population - self, whose members strive to become successful and advance in society. This leads to increased blood pressure, anxiety, obesity-associated lipid disorders, cardiov- cular diseases and diabetes. Most of these d...
The biopharmaceutical market has come along way since 1982 when the first biopharmaceutical product, recombinant human insulin, was launched. Over 120 such products are currently being marketed around the world including nine blockbuster drugs. The global market for biopharmaceuticals, which is currently valued at US$41 billion, has been growing at an impressive compound annual growth rate of 21% over the previous five years. With over one third of all pipe-line products in active development are biopharmaceuticals, this segment is set to continue outperforming the total pharmaceutical market and could easily reach US$100 billion by the end of this decade.
During the past few decades, it has become increasingly apparent that heredity is not the sole determining factor in disease development, such as cancer. This landmark work covers a wide array of aspects in the relatively new area of epigenetics, ranging from its role in the basic mechanisms of tumorigenesis, to the newest epigenetic drugs being de
The acclaimed International Review of Cytology series presents current advances and reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Contributors to this volume are - The acclaimed International Review of Cytology series presents current advances and reviews in cell biology, both plant and animal - Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth - Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research
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This book is a compilation of articles on significant events in the history of biochemistry, which were published in the journal "Trends in Biochemical Sciences." Editor Witkowski has selected articles that present an insider's view of discoveries that are now seen as landmark achievements, and that relate to the central dogma of molecular biology, which is that DNA makes RNA makes protein, or, "once information has passed into protein it cannot get out again." The book begins with Albrecht Kossel and the discovery of histones, and ranges through Schrodinger and the origins of molecular biology, the double helix, DNA replication, protein synthesis, genetic code, tRNA, mRNA, early ribosome research, peptidyl transfer, and finally to the advent of rapid DNA sequencing. Annotation : 2005 Book News, Inc., Portland, OR (booknews.com)