Welcome to our book review site www.go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
The key role of ubiquitination and sumoylation in signaling and cancer
Ubiquitination and Sumoylation are two important posttranslational modifications that play pivotal roles in a variety of biological functions. Although Ubiquitination is traditionally viewed as a critical mark targeting proteins for proteasome-dependent degradation, recent studies reveal that it also plays nonproteolytic functions. In contrast, Sumoylation is long thought not to target proteins for degradation, accumulating evidence suggests that it can serve a priming effect prerequisite for ubiquitination, thereby inducing protein ubiquitination and degradation. Thus, there is an important cross-talk between sumoylation and ubiquitination in determining protein fate. Deregulation in these two marks may cause aberrant activity of proteins and in turn contributes to cancer development. In this Research Topic, we accept review articles, perspectives, research articles covering any one or both of these two posttranslational modifications in regulating diverse signal transduction pathways and providing the novel insights in unraveling the puzzle as to how they may regulate cancer progression and metastasis.
Chat Groups in the Immortal Realm
An Sudong was originally an ordinary student, but unintentionally joined the Immortal World's chat group to make a deal with the various deities in the Heaven Realm. From then on, his life began to take off, and he wouldn't care about those rich second generations or geniuses ...
Simulation of the thermoforming process of UD fiber-reinforced thermoplastic tape laminates
In this work, initially, the requirements on a simulation model of the non-isothermal stamp forming process of unidirectional fiber-reinforced, and thermoplastic tape laminates are investigated experimentally. On this basis, different isothermal as well as a fully coupled thermomechanical simulation model under consideration of the crystallization kinetics are developed. For validation, a complex shaped geometry is simulated and compared to experimental forming results.
Incremental Sheet Forming Technologies
Incremental Sheet Forming (ISF) exempts use of dies and reduces cost for manufacturing complex parts. Sheet metal forming is used for producing high-quality components in automotive, aerospace, and medical industries. This book covers the benefits of this new technology, including the process parameters along with various techniques. Each variant of this novel process is discussed along with the requirements of machinery and hardware. In addition, appropriate guidelines are also suggested regarding the relationship between process parameters and aspects of ISF process in order to ensure the applicability of the process on the industrial scale. This book will be a useful asset for researchers, engineers in manufacturing industries, and postgraduate level courses.
Tailor Welded Blanks for Advanced Manufacturing
Tailor welded blanks are metallic sheets made from different strengths, materials, and/or thicknesses pre-welded together before forming into the final component geometry. By combining various sheets into a welded blank, engineers are able to 'tailor' the blank so that the properties are located precisely where they are needed and cost-effective, low weight components are produced. Tailor welded blanks for advanced manufacturing examines the manufacturing of tailor welded blanks and explores their current and potential future applications.Part one investigates processing and modelling issues in tailor welded blank manufacturing. Chapters discuss weld integrity, deformation during forming and...
Three Kingdoms: Iron Emperor
Lu Bu? That was my defeat! Zhao Yun? That's my senior brother! Sun Ce? He has to call me teacher! Sun Quan? When did he ever see me? A novel about modern people travelling to the Three Kingdoms, a book about a soldier stealing grain and a gun.
CRC World Dictionary of Plant Names
This volume provides the origins and meanings of the names of genera and species of extant vascular plants, with the genera arranged alphabetically from D to L.
汉英中医辞海
并列题名:Chinese-English chinese traditional medical word-ocean dictionary
Sustainable Cities Development and Environment Protection
Selected, peer reviewed papers from the 2013 International Conference on Civil, Architecture and Building Materials, (3rd CEABM 2013), May 24-26, 2013, Jinan, China
