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A thorough understanding of pathogenic microorganisms and their interactions with host organisms is crucial to prevent infectious threats due to the fact that Pathogen-Host Interactions (PHIs) have critical roles in initiating and sustaining infections. Therefore, the analysis of infection mechanisms through PHIs is indispensable to identify diagnostic biomarkers and next-generation drug targets and then to develop strategic novel solutions against drug-resistance and for personalized therapy. Traditional approaches are limited in capturing mechanisms of infection since they investigate hosts or pathogens individually. On the other hand, the systems biology approach focuses on the whole PHI ...
This book constitutes the refereed proceedings of the 10th International Conference on Intelligent Data Analysis, IDA 2011, held in Porto, Portugal, in October 2011. The 19 revised full papers and 16 revised poster papers resented together with 3 invited papers were carefully reviewed and selected from 73 submissions. All current aspects of intelligent data analysis are addressed, particularly intelligent support for modeling and analyzing complex, dynamical systems. The papers offer intelligent support for understanding evolving scientific and social systems including data collection and acquisition, such as crowd sourcing; data cleaning, semantics and markup; searching for data and assembling datasets from multiple sources; data processing, including workflows, mixed-initiative data analysis, and planning; data and information fusion; incremental, mixed-initiative model development, testing and revision; and visualization and dissemination of results; etc.
The first comprehensive, multi-specialty text on ultrasound guidance in interventional procedures, this book uses the authors' extensive clinical experience to provide a full overview of modern interventional ultrasound. For all practitioners, whether new to the procedures or already using them, Interventional Ultrasound offers expert advice and solutions to commonly encountered questions and problems. Special Features: Provides a complete approach to interventional ultrasound, beginning with essential basics on materials, equipment, setup requirements, informed consent issues, microbiologic aspects, and hygiene Covers specific, ultrasound-guided diagnostic and therapeutic interventions in t...
Chronicles life under East Germany’s GDR, the Berlin Wall’s rise, and citizens’ struggle for freedom. At midnight of 12 August 1961 East Germany became partitioned from the West by an ideological barrier that would remain a chancroid rash upon the political landscape of post WW2 Europe for some forty-five years. Initially little more than rolls of barbed wire, this barrier soon became the concrete monolith known the world over as the Berlin Wall. Prior to the construction of the wall an exodus of some 3.5 million East Germans circumvented the Eastern Bloc emigration restrictions in order to escape the socialist nightmare that many knew was now imminent. For those on the other side of t...
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