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The second edition of this text has been revised and refocused to reflect the transformation of immunotoxicology from a subdiscipline of toxicology to an independent area of research that can best be described as "environmental immunology." New chapters discuss the role of immune mediators in liver, lung, and skin toxicity, in regulating chemical- metabolizing enzymes, and in the immunosuppression produced by ultraviolet light. More emphasis is placed on the clinical consequences of immunotoxicity, as well as the interpretation of experimental data for predicting, human health risk.; The second edition is divided into three major sections: immunosuppression, autoimmunity, and hypersensitivity. This new organization of the text allows for a more thorough treatment of these phenomena, with greater attention to test methods, theoretical considerations, and clinical implications. The book includes many chapters on specific environmental agents, therapeutic drugs, biological agents, and drugs of abuse, as well as on immune-mediated toxicity in specific organ systems.
This book, commissioned by the World Health Organization (WHO) and written by international experts, provides consensus views on the most important issues related to allergic hypersensitivities. The text details predictive testing, diagnosis, epidemiological monitoring of intervention measures, sources of sensitizing agents, and mechanisms of action. Contributors extensively cover allergic hypersensitivity reactions of the skin and the respiratory system. They present the current knowledge on hypersensitivity reactions of the gastrointestinal tract and kidneys. Major gaps in existing information about allergic hypersensitivities are highlighted and recommendations for future research are given. Practical methods are provided for establishing preventive programs. Allergic Hypersensitivities Induced by Chemicals offers valuable information to both scientists and public health officials. This is a useful reference for health professionals in their work with allergies, allergens, and allergy sufferers.
A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic pathology relies heavily on the fields of both toxicology and pathology, which are well covered individually in various texts and references; however, there are few texts that address the field of toxicologic pathology. The Handbook of Toxicologic Pathology fills this void and is thus essential for all health professionals within or interacting with the field of toxicologic pathology. This two-volume set provides the reader with a single reference for toxicologic pathology. In volume I, th...
The purpose of this CD-ROM is to assist the user in making business connections with companies in Eastern Europe. At its heart is a company and product search database containing basic contact information on some 70,000 companies. American Directory Corporation has been compiling the data from thous
Dr. Marc Lappe crafts a radical new theory of immunity that stresses the concept of balance, and is remarkable for accommodating both Eastern and Western thought. This groundbreaking volume opens our minds and sets us on the path toward a healthier understanding of the body's inner forces and the difference that can mean life or death. 4 illustrations.
This volume in the Comprehensive Toxicology series demonstrates how the use of extremely powerful molecular and cell biology techniques has stimulated the growth of toxicology as a scientific discipline. The field of toxicology has evolved from its earlier days of in vivo and descriptive studies to focusing on mechanisms. Frequently, mechanisms require an examination at the cellular and molecular level. Molecular toxicology has opened the door to comprehending the basic mechanisms of how toxicants show their effects. The volume is a comprehensive, integrated profile of the molecular effects of toxicants and the molecular mechanisms involved in producing cellular and tissue injury.