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A concise, clinically oriented overview of physiology Medical Physiology: A Systems Approach offers a succinct yet thorough overview of physiology along with an introduction to basic science principles and their relevance to the clinical expression of disease. The book reflects medical education’s increased emphasis on providing students with more clinically oriented content during their first two years of medical school and the importance of the essential concepts of pathophysiology. Focused and clearly written, Medical Physiology: A Systems Approach details the major physiological processes involved in both health and disease. Each chapter begins with a list of Objectives, includes Key Concepts, and ends with Study Questions designed to test your knowledge of major concepts covered in that chapter. Most chapters also include Clinical Correlations that reinforce the major physiological principles covered and illustrate their importance to understanding disease states.
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Aim of this volume is to clarify the relationship between molecular structure and function of tight junction proteins, as well as their regulation and their role in diseases. Current research may form a basis for future diagnostic and therapeutic approaches to diseases which seem to have not much in common but are characterized by defects of organ barriers, like Crohn's disease, renal hypertension, inner ear deafness, and cancerous diseases. Topics include the functions of distinct tight junction proteins as barrier or channel formers for solutes and water, characteristics of the tight junction in inflammatory bowel diseases, posttranslational modifications of tight junction proteins, the re...
This volume draws together studies on the diverse group of calcium-activated chloride channels (CaCCS) in one comprehensive format. The characteristics of CaCCs identified in a number of different systems are described by experts in the field. Channels discussed include those described in cardiac, neuronal, endothelial and epithelial systems, in addition to sections on the CaCC of Xenopus Oocytes and the newly identified family of CLCA proteins. Key Features * Includes description of CaCCs in excitable and non-excitable tissues * Reviews identification and cloning of the CLCA protein family * Contains section on CaCCs in Xenopus Oocytes
Scientists from various disciplines integrate the neuro-biological and immunological aspects of mucosal function in the context of traditional mucosal physiological processes. Coverage includes epithelium-barrier function to antigens, lamina propria-immune and other effector cells, epithelial response to inflammation, epithelial secretory responses to inflammation, interactions of immune cells/mediators with the nervous system, neuro/immune modulation of epithelial function and pathophysiology of inflammation.
This volume represents Dr. Walker's efforts to integrate intestinal physiology and the mucosal immune system by providing the first comprehensive and systematic survey of information on the immunophysiology of the gut.