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Immune regulation at the fetal?maternal interface with focus on decidual macrophages
A successful pregnancy requires that the maternal immune system adapts to tolerate the semi-allogeneic fetal-placental unit. This adaptation mainly occurs locally, i.e. at the fetal-maternal interface, where fetal-derived tissues come into close contact with maternal cells in the uterine endometrium (called decidua during pregnancy). Macrophages and regulatory T (Treg) cells are maternal immune cells that are enriched in the decidua and they likely play a central role in promoting fetal tolerance. However, the precise function of decidual macrophages and the factors regulating both macrophages and Treg cells in humans are unknown. The aim of this thesis was to characterize the phenotype and ...
The Unchained: Powerful Life Stories of Former Slaves
This unique collection consists of the most influential narratives of former slaves, including numerous recorded testimonies, life stories and original photos of former slaves long after Civil War: Recorded Life Stories of Former Slaves from 17 different US States Narrative of the Life of Frederick Douglass 12 Years a Slave (Solomon Northup) The Underground Railroad Harriet Jacobs: The Moses of Her People Up From Slavery (Booker T. Washington) The Willie Lynch Letter: The Making of Slave! The Confessions of Nat Turner Narrative of Sojourner Truth The History of Mary Prince Running a Thousand Miles for Freedom (William & Ellen Craft) Thirty Years a Slave (Louis Hughes) Narrative of the Life o...
The Voices From The Margins: Authentic Recorded Life Stories by Former Slaves
In "The Voices From The Margins: Authentic Recorded Life Stories by Former Slaves," the Works Progress Administration delivers a poignant collection of narratives that illuminate the lived experiences of former enslaved individuals in America. This groundbreaking work, produced during the 1930s, combines oral histories with rich autobiographical accounts, providing invaluable insight into the human condition under slavery and the immense struggle for dignity and identity. The literary style is both raw and authentic, utilizing a range of dialects and personal vernaculars that enhance the readers'Äô connection with the narrators while situating their stories within the broader context of Am...
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The Memories of Slavery - Complete Collection
The Memories of Slavery - Complete Collection is an unparalleled anthology that captures the multifaceted narratives of slavery and resilience. This comprehensive collection brings together a wide range of literary styles, from poignant autobiographical accounts to incisive essays and thrilling narratives. The thematic richness is reflected in the diversity of experiences, offering profound insight into the era's social and political intricacies. Standout works provide compelling depictions of both the brutality of slavery and the indomitable spirit of those who resisted and survived. The contributing authors, including trailblazers like Frederick Douglass, Sojourner Truth, and Harriet Jacob...
Macrophages: Biology and Role in the Pathology of Diseases
Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morphogenesis and ductal branching in mammary glands. Thus, macrophages are extremely versatile cells that can respond efficiently to tissue micro environmental cues by polarizing to distinct phenotypes, depending on the functions they need to perform. Indeed, funct...
