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Prostaglandins and the Kidney
In June, 1981, we conducted a two day international symposium in Rome devoted to original scientific presentations on arachidonic acid metabolism in the kidney. Scientists from 20 countries were represented either in the general scientific program or in the poster presentation. This book does not represent the proceedings of this international gathering, but rather the edited manuscripts specifically prepared as sum maries of the scientific presentations. We feel that the timeliness and originality of the contributions as well as the need for a compilation of existing work on prosta glandins, thromboxane, and the kidney warrant this publication. The meetings would have been impossible withou...
Body Messages
Whether classified as regulators of inflammation, metabolism, or other functions, a distinctive set of molecules enables the body to convey information from one cell to another. Giamila Fantuzzi offers a primer on molecular mediators that coordinate complex bodily processes, and explores the consequences of their discovery for modern medicine.
Glucocorticoids
Following 50 years of glucocorticoid use in a clinical setting, an international body of expert scientists and physicians presents the most expansive survey of glucocorticoid pharmacology to date. This work traces the history of glucocorticoid biology from the seminal description of glucocorticoid insufficiency by Thomas Addison in the mid-19th century, up to current advances in elucidating the molecular basis of glucocorticoid action. Important discoveries are presented, as well as milestones in drug development, a survey of current clinical practice, and prospects for novel glucocorticoid-based therapeutics. Scientists and clinicians will appreciate the scope of this work, which is of special interest to workers in the fields of endocrinology, inflammation and autoimmune disease.
Relevance of Animal Studies to the Evaluation of Human Cancer Risk
Progress in Clinical and Biological Research, Volume 374 Relevance of Animal Studies to the Evaluation of Human Cancer Risk Proceedings of a Symposium held December 5–8, 1990 in Austin, Texas Robert D’Amato, Thomas J. Slaga, William H. Farland, and Carol Henry, Editors The carcinogen bioassay in rodents has been a preferred method of screening chemicals for carcinogenicity for several decades. The reliability of this methodology has recently come under scrutiny, however, raising scientific and social value issues and necessitating a re-evaluation of this approach toward assessing human risk. Relevance of Animal Studies to the Evaluation of Human Cancer Risk offers an authoritative review...
Essential and Toxic Trace Elements in Human Health and Disease
Contains up-to-date reviews on the latest advances in the role of trace elements in such areas as brain function, thymic hormone, appetite regulators, gene expression, metallothionein, free radicals and immunity. Marginal deficiency of zinc in humans, therapeutic developments in the treatment of Wilson's disease, human trace elements' requirements and analytical methods of trace elements are among the issues discussed.
Benign Prostatic Hyperplasia
This book focuses on benign prostatic hyperplasia and will include chapters on the diagnosis, epidemiology, pathogenesis, neurophysiology and treatment of the disorder.
Nanomedicine
Nanosensors and nanorobots are not science fiction but part of nanomedicine, the newest direction in medicine. After touring medical history and defining molecular nanotechnology as the atomic-level control of molecular structures to create precisely targeted medical procedures, Freitas (Institute for Molecular Manufacturing, Palo Alto, CA) details such topics as molecular transport and device applications but leaves ethical debates to others. Appends data on nanodevice design, and human blood and cell types; and a 36-page glossary. Part of a three-volume work, due to be available online. Annotation copyrighted by Book News, Inc., Portland, OR.
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