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The Chiari Malformations
This unique, contemporary book is the successor edition of a ground-breaking, authoritative title devoted to the pathology and treatment of chiari malformations. Since an abundance of research and development has occurred after the publication of the Chiari Malformations this updated title meets the market need for a reference that reflects such advances in the field. Chiari Malformations, 2nd Edition is divided into nine sections. Opening sections feature chapters on general aspects, diagnostic features and clinical presentation. These are followed by sections on differential diagnosis, treatment and prognosis. Finally, the book closes with an extensive discussion on research, related pathologies and patient resources. Expertly written chapters are supplemented with numerous high-quality illustrations and images to aid in visual learning. An impressive, nuanced successor, Chiari Malformations, 2nd Edition, is an invaluable resource for neuroscientists and clinicians at all levels, as well as graduate students to specific research scientists studying this region.
Sessional Papers
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Sessional Papers
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New Insights into Autoinflammatory Diseases: From Bench to Bedside
Systemic autoinflammatory diseases (SAIDs) are a growing group of rare disorders caused by dysregulation of the innate immune system leading to episodes of organ-specific and systemic inflammation. Autoinflammation as a distinct disease category was first reported in 1999 as a group of monogenic disorders with resultant activation of the inflammasome and cytokine excess, presenting as periodic fever and inflammation in serous membranes. Since this original description, the focus has shifted considerably to the inclusion of complex multifactorial conditions, and more than 30 associated genes have been identified. Disease severity varies from mild to life threatening. Advances in the understanding of the pathogenetic role of interleukin-1, have opened new promising horizons in the treatment of these patients, and significantly altered disease outcome.
