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Algorithms and Methods in Structural Bioinformatics
The three-dimensional structure and function of molecules present many challenges and opportunities for developing an understanding of biological systems. With the increasing availability of molecular structures and the advancing accuracy of structure predictions and molecular simulations, the space for algorithmic advancement on many analytical and predictive problems is both broad and deep. To support this field, a rich set of methods and algorithms are available, addressing a variety of important problems such as protein-protein interactions, the effect of mutations on protein structure and function, and protein structure determination. Despite recent advancements in the field, in particular in protein folding with the development of AlphaFold, many problems still remain unsolved. In this book we focus on a number of topics in Structural Bioinformatics: Cryo-EM structural detection, protein conformational exploration, elucidation of molecular binding surface using geometry, the effect of mutations, insertions and deletions on protein structural stability, and protein-ligand binding.
Man-Machine Interactions
This volume reflects a number of research streams on the development of computer systems and software that makes it possible to employ them in a variety of human activities ranging from logic studies and artificial intelligence, rule-based control of technological processes, image analysis, expert systems and decision support, to assistance in creative works. In particular, the volume points to a number of new advances in man-machine communication, interaction between visualization and modeling, rough granular computing in human-centric information processing and the discovery of affinities between perceptual granules. The topical subdivisions of this volume include human-computer interactions, decision support, rough fuzzy investigations, advances in classification methodology, pattern analysis and signal processing, computer vision and image analysis, advances in algorithmics, databases and data warehousing, and embedded system applications.
mathematical population dynamics
This book is an outcome of the Second International Conference on Mathematical Population Dynamics. It is intended for mathematicians, statisticians, biologists, and medical researchers who are interested in recent advances in analyzing changes in populations of genes, cells, and tumors.
Workshop on Branching Processes and Their Applications
One of the charms of mathematics is the contrast between its generality and its applicability to concrete, even everyday, problems. Branching processes are typical in this. Their niche of mathematics is the abstract pattern of reproduction, sets of individuals changing size and composition through their members reproducing; in other words, what Plato might have called the pure idea behind demography, population biology, cell kinetics, molecular replication, or nuclear ?ssion, had he known these scienti?c ?elds. Even in the performance of algorithms for sorting and classi?cation there is an inkling of the same pattern. In special cases, general properties of the abstract ideal then interact with the physical or biological or whatever properties at hand. But the population, or bran- ing, pattern is strong; it tends to dominate, and here lies the reason for the extreme usefulness of branching processes in diverse applications. Branching is a clean and beautiful mathematical pattern, with an intellectually challenging intrinsic structure, and it pervades the phenomena it underlies.
Man-Machine Interactions 3
Man-Machine Interaction is an interdisciplinary field of research that covers many aspects of science focused on a human and machine in conjunction. Basic goal of the study is to improve and invent new ways of communication between users and computers, and many different subjects are involved to reach the long-term research objective of an intuitive, natural and multimodal way of interaction with machines. The rapid evolution of the methods by which humans interact with computers is observed nowadays and new approaches allow using computing technologies to support people on the daily basis, making computers more usable and receptive to the user's needs. This monograph is the third edition in...
The Sarmatian Review
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Journal of the American Statistical Association
A scientific and educational journal not only for professional statisticians but also for economists, business executives, research directors, government officials, university professors, and others who are seriously interested in the application of statistical methods to practical problems, in the development of more useful methods, and in the improvement of basic statistical data.
Research Report
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