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This book brings up-to-date information on developments in studies of human stefins and cystatins, proteins with the function of cystein proteases (cathepsins) inhibition. The chapters start at the level of genes, go on with protein structure and function (proposal of alternative function), protein stability and folding, to mis-folding and mis-function. The book ends with chapters describing different disease states where stefins or cystatins are involved, from Alzheimer's disease, epilepsy to cancer.
Molecular Biology, 4/e by Robert Weaver, is designed for an introductory course in molecular biology. Molecular Biology 5/e focuses on the fundamental concepts of molecular biology emphasizing experimentation. In particular author, Rob Weaver, focuses on the study of genes and their activities at the molecular level. Through the combination of excellent illustrations and clear, succinct writing students are presented fundamental molecular biology concepts.
This book focuses on benign prostatic hyperplasia and will include chapters on the diagnosis, epidemiology, pathogenesis, neurophysiology and treatment of the disorder.
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Vols. for 1942- include proceedings of the American Physiological Society.
The study of isozymes has proven vital to understanding the genetic-enzyme structure of organisms. This volume presents an interdisciplinary review of the latest developments in this field of research. Focusing primarily on genetic and biochemical data, it covers both basic and applied aspects of isozymic biology and describes a wide range of approaches, from molecular to systemic, in the analysis of the origin, structure and function of isozymes, as well as their use and synthesis via new transgenic technology.
International contributors address some of the most exciting frontiers in molecular neurobiology that have clear implications for immunobiology and cutaneous biology. Presents the latest research on the shared signalling molecules used by the skin and the nervous and immune systems.
Progress in Clinical and Biological Research, Volume 374 Relevance of Animal Studies to the Evaluation of Human Cancer Risk Proceedings of a Symposium held December 5–8, 1990 in Austin, Texas Robert D’Amato, Thomas J. Slaga, William H. Farland, and Carol Henry, Editors The carcinogen bioassay in rodents has been a preferred method of screening chemicals for carcinogenicity for several decades. The reliability of this methodology has recently come under scrutiny, however, raising scientific and social value issues and necessitating a re-evaluation of this approach toward assessing human risk. Relevance of Animal Studies to the Evaluation of Human Cancer Risk offers an authoritative review...