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This volume brings together a range of contributors with different and hybrid academic backgrounds to explore, through bioarchaeology, the past human experience in the territories that span Mesoamerica. This handbook provides systematic bioarchaeological coverage of skeletal research in the ancient Mesoamericas. It offers an integrated collection of engrained, bioculturally embedded explorations of relevant and timely topics, such as population shifts, lifestyles, body concepts, beauty, gender, health, foodways, social inequality, and violence. The additional treatment of new methodologies, local cultural settings, and theoretic frames rounds out the scope of this handbook. The selection of 36 chapter contributions invites readers to engage with the human condition in ancient and not-so-ancient Mesoamerica and beyond. The Routledge Handbook of Mesoamerican Bioarchaeology is addressed to an audience of Mesoamericanists, students, and researchers in bioarchaeology and related fields. It serves as a comprehensive reference for courses on Mesoamerica, bioarchaeology, and Native American studies.
Ruslan Mitkov's highly successful Oxford Handbook of Computational Linguistics has been substantially revised and expanded in this second edition. Alongside updated accounts of the topics covered in the first edition, it includes 17 new chapters on subjects such as semantic role-labelling, text-to-speech synthesis, translation technology, opinion mining and sentiment analysis, and the application of Natural Language Processing in educational and biomedical contexts, among many others. The volume is divided into four parts that examine, respectively: the linguistic fundamentals of computational linguistics; the methods and resources used, such as statistical modelling, machine learning, and corpus annotation; key language processing tasks including text segmentation, anaphora resolution, and speech recognition; and the major applications of Natural Language Processing, from machine translation to author profiling. The book will be an essential reference for researchers and students in computational linguistics and Natural Language Processing, as well as those working in related industries.
New techniques for understanding animal and human interactions in the past Through case studies of faunal remains from Roman Britain, prehistoric Southeast Asia, ancient African pastoral cultures, and beyond, this volume illustrates some of the ways stable isotope analysis of ancient animals can address key questions in human prehistory. Contributors use a diverse set of isotopic techniques to investigate social and biological topics, including human paleodiets and foodways, hunting and procurement strategies, exchange patterns, animal husbandry and the genetic consequences of domestication, and short- and long-term environmental change. They demonstrate how different isotopes can be used alone or in conjunction to address questions of animal diet, movement, ecology, and management. Studies also examine how sampling strategies, statistical techniques, and regional and temporal considerations can influence isotopic results and interpretations. By applying these new methods in concert with traditional zooarchaeological analyses, archaeologists can explore questions about human ecology and environmental archaeology that were previously deemed inaccessible.
The book describes the core resources in informatics necessary to support biomedical research programs and how these can best be integrated with hospital systems to receive clinical information that is necessary to conduct translational research. The focus is on the authors’ recent practical experiences in establishing an informatics infrastructure in a large research-intensive children’s hospital. This book is intended for translational researchers and informaticians in pediatrics, but can also serve as a guide to all institutions facing the challenges of developing and strengthening informatics support for biomedical research. The first section of the book discusses important technical challenges underlying computer-based pediatric research, while subsequent sections discuss informatics applications that support biobanking and a broad range of research programs. Pediatric Biomedical Informatics provides practical insights into the design, implementation, and utilization of informatics infrastructures to optimize care and research to benefit children.
The Pacific Symposium on Biocomputing (PSB) 2015 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2015 will be held from January 4 - 8, 2015 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2015 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is...
Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.
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