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HIV-Associated Neurocognitive Disorders: Molecular and Cellular Mechanisms and Clinical Manifestations is a comprehensive volume on the field of HIV-Associated Neurocognitive Disorders (HAND) as well as its associated comorbidities. Covering clinical manifestations as well as molecular and cellular mechanisms, this book discusses available macaque and rodent animal models of HAND, epigenetic regulation, and signaling pathways underlying symptoms. Chapters also cover prevention and therapeutic strategies, as well as diagnosis and biomarkers associated with disease outcomes. This volume is appropriate for basic research and clinical investigators working in the area of HIV-1 infection. - Provides an in-depth exploration of the clinical manifestations of HAND and its comorbidities - Includes detailed assessments of the molecular and cellular mechanisms underlying HAND symptoms - Examines animal models for studying HAND, including macaque and rodent models - Presents insights into epigenetic regulation and signaling pathways implicated in HAND - Covers prevention, therapeutic strategies, and diagnostic approaches
Introduction and Perspectives This volume is based on the proceedings of the 7th annual symposium on the topic Neuroimmune Circuits, Infectious Diseases and Drugs of Abuse, Bethesda, Maryland, Oc- ber 7–9, 1999. This symposium, as in the past, focused on newer knowledge concerning the relationship between the immune and nervous systems with regards to the effects of drugs of abuse and infections, including AIDS, caused by the immunodeficiency virus. Presentations discussed the brain-immune axis from the viewpoint of drugs of abuse rather than from the subject of the brain or immunity alone. The major aim of this series of conferences has been to clarify the consequences of immunomodulation...
Nuclear Import and Export in Plants and Animals provides insight into the remarkable mechanisms of nuclear import and export. This book covers a range of topics from the nuclear pore structure, to nuclear import and export of macromolecules in plant and animal cells. In addition, the book covers the special cases of nuclear import of Agrobacterium T-DNA during plant genetic transformation, nuclear import and export of animal viruses, and nuclear intake of foreign DNA. A chapter on research methods to study nuclear transport concludes the book.
The "Progress in Cell Cycle Research" series has been conceived to serve as a collection of reviews on various aspects of a fast growing biology field, the cell division cycle. These reviews do not pretend to cover all aspects of cell cycle regulation and mechanisms but rather focus on a few topics of particular interest in the recent literature. This third volume starts with a broad overview of the diversity of ways by which viruses subdue their host cell cycle (chapter 1). Of particular interest in this area is the case of HN which has recently been extensively investigated (chapter 2). Although most of our understanding of cell cycle regulation derives from work performed in yeast and ani...
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These are the proceedings of 4th International Meeting on the Biology of Oxides, 1995. The book provides an overview of the current status of the field with contributions from over 450 specialists including the areas of enzymology, molecular cloning, and the biochemical actions of NO.
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023384299 one-volume AIDS reference annual; has become an indispensable resource covering all aspects of HIV-related disease, prevention, treatment, & education. The fourth in a series based on the most important annual AIDS conference. Book reviewers say: "An incredible amount of the latest research from all sectors." "..an interweaving of background science & conference material is invaluable." The only publication to span the whole conference, providing coverage of thousands of presentations: lectures, discussions, & posters. This edition includes not only the Florence meeting & the satellite conference on neurological complications, but also post-conference developments. PSG's in-depth r...