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Surface components in fungal cells include cell wall molecules and, in certain cases, capsular structures. In pathogens, these components are responsible for key events during interaction with the host. These events include recognition of pathogens by the immune system and generation of damage to host cells and tissues. The molecular nature of surface structures in fungi is vast and may include (glyco)proteins, polysaccharides, lipids and pigments. Many of them have been strictly associated with the antifungal immune response, as well as with steps of fungal adhesion and dissemination during interaction with host cells. For many fungal pathogens, surface composition and architecture are determinant for either disease progression or control. The diversity of the composition of the cell surface and its molecular architecture are believed to include targets for the action of new antifungals, as well as immunogens with potential to interfere with fungal diseases in favor of the host.
The current volume focuses on novel sources of biofungicides, primarily providing complete knowledge of microbial and phytochemical fungicides, studying antifungal activity mechanisms as well as their role in disease management in plants, and fungicide bioremediation. The use of biofungicides as eco-friendly alternative to typical synthetic fungicides is projected to play a significant role in organic farming in the future. Key Features: Discovers novel sources of biofungicides Describes the role of biofungicides in the control of plant diseases Studies antifungal activity mechanisms Explores how to survey and select promising biofungicides
The sequencing of several fungi genomes has spurred major advances in the field. Fungal genomics has been having a pivotal impact on applied research in agriculture, food sciences, natural resource management, pharmaceuticals, and biotechnology, as well as to basic studies in the life sciences. Fungal Genomics covers exciting new developments in this growth field, from genomic analysis to human fungal pathogen genomics, comparative genomics of fungi, and the genomics of fungal development. - Includes information on aspergillus genomes - Discusses sex and its role in virulence of human fungal pathogens - Covers the genomic analysis of neurospora
The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Volume 85 presents an eclectic mix of articles of use to all human and molecular geneticists on topics including: association mapping in crop plants; miRNA-mediated crosstalk between transcripts; unisexual reproduction; and more. - Includes methods for testing with ethical, legal, and social implications - Critically analyzes future directions - Written and edited by recognized leaders in the field
Section 1: DNA metabolism; Chapter 1: Prokaryotic DNA replication. Chapter 2: DNA repair mechanisms and mutagenesis. Chapter 3: Gene expression and its regulation. Chapter 4: Bacteriophage genetics. Chapter 5: Bacteriophage and its relatives. Chapter 6: Single-stranded DNA phages. Chapter 7: Restriction-modification systems. Chapter 8: Recombination. Chapter 9: Molecular applications. Section 2: Genetic response. Chapter 10: Genetics of quorum sensing circuitry in Pseudomonas aeruginosa: Implications for control of pathogenesis, biofilm formation, and antibiotic/biocide resistance. Chapter 11: Endospore formation in Bacillus subtilis: an example of cell differentiation by a bacterium. Chapte...