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Phospholipases in Physiology and Pathology presents a comprehensive overview on the physiology and pathology of phospholipases. This seven-volume set considers the biochemical and molecular mechanisms of normal and abnormal cell function upon dysregulation of phospholipases in different diseases. Volumes cover signal transduction mechanisms, implications in cancer, infectious diseases, neural diseases, cardiovascular diseases and other diseases, implications in inflammation, apoptosis, gene expression and non-coding RNAs, the role of natural and synthetic compounds, and stem cell therapies, nanotechnology-based therapies, and more. Together, these volumes give researchers critical insight on the mechanistic and therapeutic aspects of phospholipases. - Discusses the biochemical and molecular mechanisms of normal and abnormal cell function in different disease processes - Covers a wide range of basic and translational research appropriate for scientists engaged in studying the regulation of phospholipases from interdisciplinary perspectives - Features state-of-the-art chapter contributions from international leaders in the field
This special issue of Molecular and Cellular Biochemistry contains original research articles and review papers which were invited from the participants of a recent meeting organized to honour the 60th birthday of Naranjan S. Dhalla, Ph.D., M.D.(Hon.). The meeting, organized by Drs. Morris Karmazyn (London), Grant Pierce (Winnipeg) and Balwant Tuana (Ottawa), was held at the Best Western Lakeside Inn in Kenora, Ontario, Canada on August 23-25, 1996. The meeting was entitled The Cellular Basis of Cardiovascular Function in Health and Disease. There were over 40 invited speakers from 15 different countries represented at the meeting, attended by over 280 people. Keynote lectures were presented...
Pharmacology is a rapidly progressing area of biomedical research, with new developments surfacing at regular intervals, constantly revolutionizing drug therapy for disease states. The interaction of this discipline with other biomedical sciences has opened up new vistas and opportunities in drug design and development. Basic and clinical concepts in the mechanism and use of drugs are carefully integrated into hypotheses, which are aimed at the maintenance of a critical balance between health and disease. Current Trends in Pharmacology is a comprehensive collection of topics highly significant in the current health scenario. The book comprises a combination of articles in clinical and experi...
First multi-year cumulation covers six years: 1965-70.
Focused extensively on the toxic effect of chemicals on the cardiovascular system, Cardiovascular Toxicology, Fourth Edition is comprised of several key sections beyond cardio- and vascular toxicity, such as principles of myocardial cell injury and key methods of assessing cardiovascular function. New developments include: an expanded chapter on passive smoking, which includes the adverse effects of both first-hand smoking and secondary smoke inhalation a new chapter on the negative effects of environmental chemicals on the cardiovascular system chapters covering antibacterial agents and endotoxins that include new information on cardiovascular toxicity of antimicrobials, as well as anti-viral agents, antibacterial agents, and other agents