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The Charnolosome as a Novel Nanothereranostic Biomarker
The Charnolosome as a Novel Nanothereranostic Biomarker: Overcoming Future Challenges in Medicine provides an overview of the charnolosome and its potential as a biomarker of cell injury. Based on the author's original discovery of the charnoly body in the developing, undernourished rat cerebellar Purkinje neurons, this book delves into the potential for utilizing this mitochondria and lysosomal-derived intracellular organelle as a nanotheranostic biomarker to prevent and cure various diseases.The book discusses the cellular, molecular, genetic, and epigenetic mechanisms of charnolosomes and charnolosome-derived nano-vesicles. It also investigates the molecular mechanisms underlying auto-inf...
Quiet Quitting and the Leadership Challenge
In this timely book, Cam Caldwell, Verl Anderson and Dima Jamali explore the concept of ‘Quiet Quitting’ and its role in business. They focus on what employers and the business community can productively do to reverse the Quiet Quitting phenomenon, while honoring their responsibilities to employees.
Promoting Holistic Development in University Students
This book focuses on the issue of holistic development of university students. It takes a specific focus on the developmental needs of the students and the importance of the development of twenty-first-century skills, as well as well-being, leadership, and civic engagement in university students. Drawing from the case study of the “Leadership Education and Development” (LEAD) program in Hong Kong, the author outlines existing theories, research findings, and best practices in the promotion of university students' development. Particularly relevant to social scientists and practitioners in higher education settings, not only in Hong Kong and China, but beyond, this book is a pioneer and substantial contribution to the fields of youth studies, positive psychology, quality of life and well-being.
Charnolophagy in Health and Disease
This book introduces charnolophagy (CP) as energy-driven, lysosomal-dependent mitochondrial inclusion-specific pleomorphic Charnoly body (CB) autophagy (ATG) involving free radical-induced Ca2+ dyshomeostasis, ΔΨ collapse, and ATP depletion in congenital diseases, pressure ulcers, metabolic diseases, hepatic diseases, diabetes, obesity, inflammatory diseases, musculoskeletal diseases, sarcopenia, cachexia, respiratory diseases, gastrointestinal diseases, hyperlipidemia, skin and hair diseases, pulmonary diseases, cardiovascular diseases, renal diseases, sepsis-induced multi-organ failure, reproductive diseases, inflammatory diseases, ophthalmic diseases, neurodegenerative diseases, drug ad...
Phase-Transformation Stresses in Composite Materials I
This monograph presents original mathematical models of phase-transformation stresses, which originate in isotropic matrix-inclusion composites during a cooling process, along with mathematical models of material micro-/macro-strengthening, as well as mathematical models of inter-/transcrystalline crack formation, which are induced by theses stresses, including mathematical definitions of critical limit states with respect to the material crack formation. The material strengthening and the limit states represent important phenomena in material science and engineering. The mathematical models are determined for two types of real two-component materials, which consist of isotropic ellipsoidal ...
Applied Research in Hydraulics and Heat Flow
Applied Research in Hydraulics and Heat Flow covers modern subjects of mechanical engineering such as fluid mechanics, heat transfer, and flow control in complex systems as well as new aspects related to mechanical engineering education. The chapters help to enhance the understanding of both the fundamentals of mechanical engineering and their application to the solution of problems in modern industry. The book includes the most popular applications-oriented approach to engineering fluid mechanics and heat transfer. It offers a clear and practical presentation of all basic principles of fluid mechanics and heat transfer, tying theory directly to real devices and systems used in mechanical an...
Applications of Measure Theory to Statistics
This book aims to put strong reasonable mathematical senses in notions of objectivity and subjectivity for consistent estimations in a Polish group by using the concept of Haar null sets in the corresponding group. This new approach – naturally dividing the class of all consistent estimates of an unknown parameter in a Polish group into disjoint classes of subjective and objective estimates – helps the reader to clarify some conjectures arising in the criticism of null hypothesis significance testing. The book also acquaints readers with the theory of infinite-dimensional Monte Carlo integration recently developed for estimation of the value of infinite-dimensional Riemann integrals over infinite-dimensional rectangles. The book is addressed both to graduate students and to researchers active in the fields of analysis, measure theory, and mathematical statistics.
Who Shaped Science Fiction?
This book combines the reading public's interest in science fiction with the always popular biography genre. The book contains one hundred concise chapters, each containing a brief biography of one of the most influential figures in the development of modern science fiction as well as a timetable detailing the highlights of the person's life and career. Included are important editors such as John Campbell Jr and Hugo Gernsback; filmmakers such as Gener Roddenberry and Stanley Kubrick; and most importantly, acclaimed writers ranging from historical figures Jules Verne, Edgar Allen Poe, Arthur Conan Doyle, and H G Wells to modern masters Arthur Clarke, Isaac Asimov, and Robert Heinlein.
