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Based on presentations made during the 6th International Symposium on Natural Product Chemistry, this book is divided into two broad sections. Section A includes articles on synthetic routes developed to complex natural products, while Section B is a compilation of discoveries of new natural products and their pharmacological properties. There are several chapters devoted to various advances in the ongoing quest for improved anticancer agents from natural sources, be they from plants, marine organisms or microorganisms. Approaches to the development of new antimalarial agents are reviewed, as are strategies for cancer chemopreventive agents.
Increasing scientific evidence suggests that the majority of diseases including cancer are driven by oxidative stress and inflammation, attributed to environmental factors. These factors either drive genetic mutations or epigenetically modify expression of key regulatory genes. These changes can occur as early as gestational fetal development, and
Progress in Photochemistry, Volume 5 is collection of papers that covers studies in the chemical aspects of botany. The title first coves the osmotic regulation in algae, and the proceeds to tackling the biochemistry of host response to infection. Next, the selection deals with biosynthesis of monoterpenes and chlorophyll biosynthesis and its control. The text also details the chemical constituents of the bryophytes, along with the anticancer agents from plants. The book will be of great interest to botanists, biochemists, and natural product chemists.
Plant Secondary Metabolism presents a basic understanding of the origin of the compounds, the nature of the precursors involved, and the basic reactions, mechanisms, and stereochemistry. The origin of groups of secondary metabolites is linked to evolutionary principles, and their biological activity is viewed in a context of chemical ecology. Topics are treated comprehensively, enabling the reader to understand not only a particular group of compounds, but also how each group fits into the whole. In addition, the text allows readers to systematically survey various secondary metabolites and gain a quick working knowledge, which can be applied to problems in a particular field. Those researchers and students who will be most intrigued by this publication's broad overview on plant secondary metabolites come from a diverse range of disciplines, including agronomy, anthropology, biochemistry, biology, botany, chemistry, ecology, entomology, food science, forestry, geology, horticulture, pharmacognosy, plant biology, plant sciences, toxicology, and zoology.
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This book provides a detailed, practical and, where possible, research-based rationale for the use of herbal treatments in a wide variety of clinical conditions and problems. Through the filter of current scientific literature, the authors have reevaluated traditional use of herbal remedies and present realistic guidelines for modern practice. A uniquely authoritative guide to applying herbal medicines as serious options for the treatment of some of the most troublesome conditions seen today. In particular, this book gives: * A clear description of the principles and foundations for the practice of phytotherapy * In-depth and detailed profiles of over 45 herbs, reviewing pharmacology, research, and traditional use * Therapeutics for actual disease states, supported by case histories *Coverage of challenging issues such as dosage, safety, and drug-herb interactions