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Enzymatic Basis of Detoxication, Volume II, reviews the state of knowledge on foreign compound metabolism at the level of what specific enzymes can do. The book attempts to provide a holistic view of the information gleaned from work with specific, purified enzymes encompassing as many mammalian sources as have been studied. The book is organized into two parts. Part I on conjugation reactions and related systems includes studies on the properties of glucuronide formation; the physiological function, assay, and purificatgion of function of bilirubin-glucuronoside glucuronosyltransferase; the roles of N- and O-methylation reactions and glutathione transferases in detoxication; and amino acid conjugation. Part II presents studies on hydrolytic systems, covering the role of epoxide hydrolase, carboxylesterases, and amidases in detoxication and the regulatory effects of these enzymes. This book provides pharmacologists and toxicologists with the biochemical view of detoxication, and biochemists with the corresponding pharmacological and toxicological aspects.
The API (Association of Physicians of India) Textbook of Medicine consists of 28 sections across two comprehensive volumes covering a wide range of medical disorders. Fully revised and with 1588 images, illustrations and tables, this new edition has many new chapters on topics including nanotechnology and nano-medicine, and clinical approach to key manifestations. Each section is dedicated to a different medical phenomenon, including clinical pharmacology, endocrinology, dermatology, infectious diseases and nutrition. Also included is online access to teaching modules for teachers and students, questions and answers, an atlas/image bank, echocardiography and video EEG and common medical procedures with voice over.
Enzymatic Basis of Detoxication, Volume I focuses on the catalytic mechanisms and physiological expression of the enzymes that are involved in the detoxication of foreign compounds. The book explores foreign compound metabolism at the level of what specific enzymes can do. This book is organized into three sections and comprised of 17 chapters. The discussion begins with an overview of detoxication and covers both catalytic and non-catalytic removal of foreign substances, along with the general properties of the enzymes that are active in detoxication. The reader is then introduced to the physiological aspects of detoxication, paying particular attention to the kinetic aspects of metabolism ...
Each vol. consists of papers reprinted from various periodicals, etc.
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