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Host-pathogen crosstalk: implications in host cellular processes by intracellular pathogens
Infectious diseases are still leading cause of mortality around the world. Of particular importance in this regard are the intracellular pathogens, which dwell inside the host and manipulate host’s machinery for their growth. These include pathogens like Brucella abortus, Listeria monocytogenes, Chlamydia trachomatis, Coxiella burnetii, Mycobacterium tuberculosis, Salmonella enterica, etc. These pathogens have evolved multiple mechanisms to survive in intracellular niche. The host in turn tries to reprogram its activities to combat their growth. This host-pathogen co-evolution warrants detailed study to probe the ever-changing virulence repertoire of the pathogen, that can be used for pathogen targeting. Through this topic, we would like to explore the lesser explored area of host pathogen interactions. Studying host-pathogen crosstalk at their interface will help us in understanding this complex biology and might prove beneficial in development of new therapeutic targets. Understanding the holistics of host-pathogen interaction, will pave way for development of host-directed therapies.
Expert Opinions: Save the Microbes to Save the Planet
With over a trillion species of microorganisms populating our planet, their crucial role in sustaining life and maintaining habitability cannot be overstated. However, a mere fraction of these microorganisms, about 1400 species, contribute to infectious diseases that pose significant risks to human health, leading to pandemics and economic losses. We are calling for global development of sustainable solutions that control infectious agents while safeguarding global microbial diversity and the well-being of our planet. This Research Topic is launched in collaboration with the International Union of the Microbiological Societies (IUMS) ahead of IUMS 2024 - Microorganisms for sustainable soluti...
Chaff and Grain
A PIONEERING WORK ON A highly topical subject, Chaff and Grain: Guilt, Innocence and the Dilemmas of Justice by Vivek Sood goes into the malfunctions of the criminal justice system in India. The Supreme Court has gone to the extent of saying that in our criminal justice system the judge presiding over a trial decides on the basis of his sixth sense as to what must have happened during the incident and then lays his trust in God and good luck for coming to the 'right' conclusion. In this hard-hitting take on the criminal justice process, Sood delves into how the innocent end up as undertrials, the misuse of the power of arrest by the police, unjustified denial of bail, manipulated investigati...
Women in Microorganisms in Vertebrate Digestive Systems: 2023
Please note that to be considered for this collection, the first author or at least one corresponding author should be a researcher who identifies as a woman. After the well-received 2022 collection, Frontiers in Microbiology is proud to host this Research Topic celebrating women’s work and achievements in the field of Microorganisms in Vertebrate Digestive Systems. Alongside International Women’s Day and Women’s History Month 2023, we will collectively embrace equity in the microbiology community. There is continued gender disparity within core STEM subjects. According to UNESCO Institute for Statistics, just 33% of the world's researchers are women. While the number of women attendin...
