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Targeting Autophagy in Cancer Therapy
This volume will detail the current state and perspectives of autophagy-based cancer therapy. Covering a wide range of topics, it will include an overview of autophagy as a therapeutic target in cancer, autophagy modulators as cancer therapeutic agents, implications of micro-RNA-regulated autophagy in cancer therapy, modulation of autophagy through targeting PI3 kinase in cancer therapy, targeting autophagy in cancer stem cells, and roles of autophagy in cancer immunotherapy. In addition, the volume will review applications of system biology and bioinformatics approaches to discovering cancer therapeutic targets in the autophagy regulatory network. The volume will be beneficial for a variety of basic and clinical scientists, including cancer biologists, autophagy researchers, pharmacologists, and clinical oncologists who wish to delve more deeply into this field of cancer research. This volume will be the first book to focus solely on autophagy as a target in cancer therapy. As well, it will comprehensively discuss the roles of autophagy in most currently available cancer treatments.
Medical Mycology in the United States
The development of medical mycology in the United States is assessed within the context of scientific progress as demonstrated by the creativity and scholarly contributions from research, technological activities, and training toward the management of fungal diseases. Although it focuses on American figures and events, it covers the origins of the discipline in Europe and Latin America. It describes historically significant scientific, technological and educational development and the narrative description is accompanied by an analysis of the causes of these and their perceived impact on the development of the discipline from the late 1880s into the 1990s. The development was conceptualised into five aras: the era of discovery, the formative years, the advent of antifungal and immunosuppressive therapies, the years of expansion and the era of transition.
Alcohol-Associated Liver Disease - From Pathogenesis to Treatment
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Operating Within the Shadows
Mick Cutler is a self-reliant young man recently separated from his special forces background and a past of fast-paced and dangerous clandestine activities he wishes to forget. Soon to be married, he now lives his dream enjoying a quiet small-town life, offering his sailboat and its captain for tourist cruises or fishing charters. His fiance, Kate, disappears leaving no trace and few clues. Mick begins a frantic search teaming with two strangers. Their travels lead from one shore to the other, upon secret military bases, into rural mountain seclusion, and peaceful coastal resorts to our divergent government operating within the shadows. If you enjoy a book filled with fast-paced action-adventure or a surprising mystery thriller, you will enjoy Operating Within the Shadows!
Decision Making in Spinal Care
A comprehensive and concise reference for determining treatment options of the spine Updated and expanded to reflect current management strategies and new technologies, Decision Making in Spinal Care, Second Edition provides readers with focused guidance to every major topic in spine, with an emphasis on clinical decision making. Covering the most common spine problems, this new edition covers the spectrum of diagnoses seen in a typical spinal practice, from trauma injuries to metabolic and degenerative diseases to spinal deformities. Highlights of the Second Edition: Focuses on "must-know" information that significantly impacts clinical decisions Includes new spinal technologies in the Contemporary Topics section to keep readers current Contains more algorithms, figures, and diagrams to aid understanding and facilitate rapid management guidance Written by world-renowned spinal care experts This handy portable reference will enable residents, fellows, spine surgeons, and associated clinicians in orthopedic surgery and neurosurgery to quickly access the information they need to make the right decisions in treating typical spinal conditions.
ASM News
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Connecticut Reports
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Frontier
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