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Gaba in Autism and Related Disorders
Gamma-aminobutyric acid (GABA) was discovered in the brain in 1950 by Eugene Roberts. GABA is now considered one of the most important neurotransmitters and developmental signals. Knowledge on the complexity of GABA function is increasing exponentially. This volume covers basic research on GABA in the developing brain as it may relate to onset of autism and related developmental disorders. The evidence that dysfunction of GABA and related molecules is associated with autism is limited but expanding and seems to converge. Pertinent data are reviewed in this book and new research avenues in the basic and clinical arenas are described. The topics are of imminent interest to basic and clinical researchers as well as interested clinicians. * Discusses the neuropathology of the GABA system in autism * Presents new findings on common genetic mechanisms in Rett syndrome, Angelman syndrome, and autism * Includes information on the shared genetic risk factors between autism and major mental disorders * Foreword by Eugene Roberts
The Neurobiology of Autism
In the decade since the first edition of The Neurobiology of Autism was published, tremendous advances have been made in our understanding of autism, including more precise investigations into the role played by genetics and abnormalities in such neurotransmitters as acetylcholine and serotonin. For this long-anticipated new edition, neurologists Margaret L. Bauman and Thomas L. Kemper bring together leading researchers and clinicians to present the most current scientific knowledge and theories about autism. Thoroughly updated, The Neurobiology of Autism remains the best single-volume work on the wide array of research being conducted into the causes, characteristics, and treatment of autism. Topics addressed include epidemiology of autism; language and communication disorders in autism spectrum disorders; approaches to psychopharmacology; structural brain anatomy in autism; myelin and autism; positron emission tomography studies in autism; gene expression in autism; candidate susceptibility genes for autism; Fragile X syndrome; norepinephrine and serotonin in autism; and the immune system.
Astrocytes
This is a second edition of a book that provides an overview of the most current findings on the diverse roles played by astrocytes in the function and dysfunction of the central nervous system (CNS), with emphasis on their cellular connections. Astrocytes are highly elaborated cells and likely the only neural cells that simultaneously establish associations with different cellular types. The fine processes of astrocytes are found in practically all nearby cellular types in the CNS, including astrocytes themselves, neurons, oligodendrocytes, microglia, and brain endothelial cells. Such close morphological associations, together with the fact that astrocytes express a multitude of ion channels, transporters, and membrane receptors, endow these cells with the unique capability to sense and influence diverse CNS functions. Disruption of these elaborated connections and altered astrocyte polarization are implicated in numerous pathological conditions, such as epilepsy, stroke, leukodystrophies, Alzheimer’s, and autism, and also certain psychiatric disorders, major depression, and schizophrenia.
Psychopharmacology
Provides an overview of today's psychopharmaceuticals, their therapeutic uses, adverse effects and limitations. An account of the history of psychopharmacology is followed by detailed descriptions of current research in animals and humans aimed at developing even more effective and safe medications. Concepts of pharmacokinetics and pharmacodynamics, including so-called mechanisms of action of psychopharmaceuticals, are explained. Advanced techniques such as SPECT, PET, and fMRI and their uses in psychopharmacology research are described. The book also provides a critical discussion of the relationship between drug-based and non-drug based therapies for mental disorders and addresses economic aspects of psychopharmacology.
Current Diagnosis & Treatment in Psychiatry
This book covers the diagnosis, psychopharmacologic treatment, and psychotherapeutic management of the full range of psychiatric disorders. It includes a separate section devoted to psychiatric disorder occurring in infancy, childhood, and adolescence. (Midwest).
Conn's Current Therapy 1997
Exploring the important advances and popular therapies for the most frequently debated and treated conditions, this text delivers more than 1000 therapies for over 300 medical conditions. It also includes information on the latest drugs.
Current Psychiatric Therapy II
A comprehensive update of psychiatric disorders and their treatment. This 2nd Edition defines treatment in terms of DSM-IV. Features chapters on personality testing and cross-cultural issues as used in psychopharmacology, treatment in the primary care setting, and medication usage during pregnancy.
Current Biography
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