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The Lure of Bacterial Genetics
A unique, rigorous scientific approach to understanding bacterial genetics • Provides a complete overview of the entire field of bacterial genetics, helping the reader to understand how the field has evolved. • Inspires readers by providing an opportunity to learn from John Roth’s achievements and contributions to bacterial genetics. • Offers valuable lessons in the history and science of bacterial genetics by providing a behind the scenes look at some of the most important triumphs and mishaps that have occurred on the path to discovery.
Modulating Prokaryotic Lifestyle by DNA-Binding Proteins
The Overview of the Topic was the following: "One of the most active areas of research in molecular microbiology has been the study of how bacteria modulate their genetic activity and its consequences. The prokaryotic world has gained a lot of interest. In addition to the above, the invention is based on the subject-matter of the present invention, which is incorporated herein by reference in its entirety. All of these processes are fundamental to the operation of a genetic entity and condition their lifestyle. Further, the discoveries in the bacterial world have been of ample use in eukaryotes. [Article in German] Hansen, Hansen, H. (2003). In addition to the fundamental interest in underst...
From Chromosomes to Mobile Genetic Elements
This biography of Nobel Laureate Barbara McClintock (1902-1992) places her life and work in its social, scientific and personal context. The author examines the development of Barbara McClintock’s scientific work and her influence upon individuals and upon the fields of cytogenetics and evolutionary biology in the period from 1902 to the present. The history documents years of McClintock’s notable and lauded scientific work long before she discovered and named transposable elements in the mid-1940s for which she ultimately received the Nobel Prize. The biography employs documented evidence to expose, demystify, and provide clarity for legends and misinterpretations of McClintock’s life and work. Key Features Exposes and demystifies myths and legends told about McClintock’s time in Missouri Clarifies the changing language of genes and genetics Places in perspective the history of McClintock’s research Documents McClintock’s family and early life before college Provides documented details of McClintock’s time in Nazi Germany
DNA Microarrays, Part B: Databases and Statistics
Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshoot...
Laboratory Methods in Enzymology: Cell, Lipid and Carbohydrate
Methods in Enzymology volumes provide an indispensable tool for the researcher. Each volume is carefully written and edited by experts to contain state-of-the-art reviews and step-by-step protocols. In this volume, we have brought together a number of core protocols concentrating on Cell, Lipid and Carbohydrate, complementing the traditional content that is found in past, present and future Methods in Enzymology volumes. - Indispensable tool for the researcher - Carefully written and edited by experts to contain step-by-step protocols - In this volume we have brought together a number of core protocols concentrating on Cell, Lipid and Carbohydrate
Proteins: Structure, Function, and Engineering
Here, researchers review the latest breakthroughs in protein research. Their contributions explore emerging principles and techniques and survey important classes of proteins that will play key roles in the field's future. Articles examine the possibility of a Boltzman-like distribution in protein substructures, the new technique of Raman spectroscopy, and compact intermediate states of protein folding. This well-illustrated volume also features coverage of proteins that bind nucleic acids.
