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Cardiovascular Eponymic Signs
This book proposes a novel learning approach that complements and augments the prevailing method of case-based learning. Learning these signs requires the application and integration of the fundamental skills of observation, palpation, percussion, and auscultation, and in more advanced cases, the use of maneuvers performed at the patient’s bedside. The book provides a discussion of the utility of the signs and reviews the mechanism and pathophysiology of related cardiovascular diseases. Each chapter discusses eponymic signs for a variety of cardiovascular diseases such as atherosclerosis, heart failure, hypertension, venothromboembolism, ischemic heart disease, pericarditis, and peripheral...
Autophagy at the Cell, Tissue and Organismal Level
This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.
Systemic Lupus Erythematosus
Systemic Lupus Erythematosus combines basic science with clinical science to provide a translational treatment of the disease and is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries. - Provides the very latest overview of the pathogenesis of SLE - Distills current understanding of the cellular, molecular, genetic and environmental factors that instigate and drive the disease - Includes comprehensive coverage of clinical features, including fatigue, organ system manifestations, overlap syndromes, infections, and more - Conveys the very latest understanding of mechanisms of tissue damage, including immune complexes, antibodies, and other mechanisms that lead to organ damage - Discusses the latest treatment options on disease modifying or disease controlling agents - Provides 'one stop' coverage of all the latest scientific and clinical developments in SLE
The Medical Mandarins
This wide-ranging and imaginative book examines the social and scientific role of the French Academy of Medicine from its creation in 1820 to the outbreak of the Second World War. It employs academic activities and sources to explore such major questions in the social and scientific history of medicine as the nature of therapeutic reasoning, the specificity of French medicine, and the consequences of hierarchial centralization for the medical profession.
Rarer Arthropathies
This volume on Rarer Arthropathies, part of the series "Rare Diseases of the Immune System" aims to fill a gap in the literature by informing and updating clinicians on the unusual and uncommon forms of arthritis and related musculoskeletal conditions. It will be a valuable go-to resource for clinicians to support them in differential diagnosis, in particular when facing unusual presentations. Nineteen chapters written by experts have covered a wide range of these conditions, providing first rate information on topics yet lacking adequate coverage; from Palindromic Rheumatism to SAPHO Syndrome and other chronic immune-mediated conditions, while also including arthritis in leprosy, tuberculos...
