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In recent decades, there has been an explosive growth in knowledge on the important biological roles of carbohydrates, especailly as specific information carriers. Neoglycoconjugates have been indispensable tools in these studies. This timely book, with both synthetic and application studies, will be of great value to researchers in a number of disciplines. - Includes applications of neoglycoconjugates in medicine (vaccine preparation, drug targeting and tumor diagnosis) - Is a comprehensive survey of synthetic strategies - Covers application of neoglycoconjugates in basic research
The present understanding of the various implications of lectins in pathology are summarised in this timely text. With contributions from leading investigators in the field of lectin research, Lectins and Pathology provides up-to-date information on key developments within this field, including the use of lectins and lectin-binding molecules as tools, the involvement of endogenous (animal or human) lectins in inflammation, cancer invasion and metastasis, as well as the importance of lectins in bacteriology and parasitology. This volume contains useful knowledge for clinical investigators, cell biologists, biochemists and biotechnologists, as well as for the graduate students interested in getting a comprehensive coverage of this field.
"Habe ich eine Chance? Soll ich diese Therapie machen?" Hausärzte stehen an der Schnittstelle zwischen behandelnden Fachärzten und onkologischen Patienten und müssen sich mit solchen Fragen beschäftigen. Sie sind für ihre Patienten die wichtigsten Unterstützer und Lotsen durch die Phasen von Diagnose, Therapie und Nachsorge einer Krebserkrankung. Das Buch behandelt unter anderem folgende Themen: - Genetische Grundlagen einer Tumorerkrankung - Risikofaktoren für Krebs und Vermeidungsmöglichkeiten - Die wichtigsten Diagnoseverfahren - Behandlung der häufigsten Nebenwirkungen von Tumortherapien wie Infektionen, Übelkeit und Schmerzen - Onkologische Notfälle wie Atemnot, Blutungen, Se...
Molecular nanotechnology has been defined as the three-dimensional positional control of molecular structure to create materials and devices to molecular precision. The human body is comprised of molecules, hence the availability of molecular nanotechnology will permit dramatic progress in human medical services. More than just an extension of "molecular medicine," nanomedicine will employ molecular machine systems to address medical problems, and will use molecular knowledge to maintain and improve human health at the molecular scale. Nanomedicine will have extraordinary and far-reaching implications for the medical profession, for the definition of disease, for the diagnosis and treatment of medical conditions including aging, for our very personal relationships with our own bodies and ultimately for the improvement and extension of natural human biological structure and function. This book will be published in three volumes over the course of several years. Readers wishing to keep up-to-date with the latest developments may visit the nanomedicine website maintained by the Foresight Institute (http://foresight.org/Nanomedicine/index.html).
Neoglycoconjugates are not only useful for the basic understanding of protein-carbohydrate interactions, but they have many practical applications as well. They are powerful reagents in many cell biology studies and excellent tools for the isolation and characterization of animal and plant lectins, separation of cells, as well as for the targeting of drugs, artificial vaccines, and diagnostic reagents. Volume 247 and its companion Volume 242 contain many practical methods on how to prepare and use neoglycoconjugates. Volume 242 deals with synthesis and 247 with biomedical applications.
First multi-year cumulation covers six years: 1965-70.
Neoglycoconjugates are important tools in the study of the biological roles of carbohydrates. This book provides a survey of synthetic strategies for neoglycoconjugate production and includes applications in medicine, particularly in vaccine preparation, drug targetting and tumour diagnosis.
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