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DNA Repair and Mutagenesis in Eukaryotes
Not many years ago most discussion of mutation induction by physical and chemical agents concentrated on the initial lesions induced in the DNA with the implicit assumption that once the lesions were made they were converted almost automatically to mutations by relatively simple processes associated with DNA replication. The discovery of a variety of enzymatic processes that can repair these lesions, the great increase in our understanding of the molecular steps involved in repair, replication, and recombination, and the increasing availability of cells with genetic defects in these pro cesses have led to the realization that mutation induction is a far more complex process than we originall...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
DNA Synthesis
This book represents the proceedings of the NATO Advanced Study Institute held in Santa Flavia, Sicily from the 20 - 29th June, 1977. In addition to the review talks given by the Lecturers at the Institute it proved feasible for other topics to be splendidly reviewed. This has led to a much wider subject coverage than would otherwise have been possible. The discussion sessions which followed these review talks were extremely valuable and almost all the participants played an active role. Essentially all of the verbal contributions presented at this ASI were subsequently put into written format, which is why these proceedings are so extensive. ~hey do, however, provide an up-to-date summary o...
Aging and Cellular Defense Mechanisms
This volume shows how defence mechanisms such as DNA repair, production of heat shock and other stress proteins, enzymatic and non-enzymatic antioxidant defence systems, and poly (ADP-ribose) polymerase activation constitute an integrated network of critical importance for the aging process. There is an emphasis on growth factor deprivation and programmed cell death, and on the nervous and immune systems, in the framework of a molecular biology approach.
Annals of the New York Academy of Sciences
Records of meetings 1808-1916 in v. 11-27.
