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Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of treatment approaches for breast cancer, including conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies. This book compiles the most important information on the state-of-the-art therapeutics, including breast cancer biomarkers and design principles of bio-responsive nanosystems. Presented in two parts, sections cover basic and receptor mediated targeting approaches and examine tumor microenvironment mediated approaches. This is a useful book for pharmaceutical scientists and basic and clinical scientists working in the research ar...
Inorganic Biomaterials for Drug Delivery covers a wide range of inorganic biomaterial types and their properties, from traditional materials like ceramics, metallics, and bioglasses to novel composites and nano-engineered inorganic biomaterials. Biocompatibility, toxicity, and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science, pharmacology, chemical engineering, and clinical science. - Comprehensively covers all key inorganic biomaterial classes for drug delivery, providing a one-stop-shop for readers - Considers both traditional inorganics and novel nanobiomaterials, offering a balanced approach - Written by a global team of experts from a range of related fields, offering a diverse, interdisciplinary guide to inorganic biomaterials for drug delivery
Ligands for Targeted Drug Delivery: Basic Fundamentals and Applications is a comprehensive reference focused on the many ways drug carriers can be functionalized to target specific organs, tissues, cells, and sub-cellular compartments. Chapters cover the basic concepts of targeted drug delivery, describing multiple levels of targets and challenges, along with approaches for target-specific drug delivery and a thorough overview of the challenges in design and application of ligands. Following sections discuss nanoparticles and the main ligand classes with their respective applications. The final chapters discuss future prospects of the technology and clinical aspects of ligand modified drug d...
Functionalized polymers are macromolecules to which chemically bound functional groups are attached which can be used as catalysts, reagents, protective groups, etc. Functionalized polymers have low cost, ease of processing and attractive features for functional organic molecules. Chemical reactions for the introduction of functional groups in polymers and the conversion of functional groups in polymers depend on different properties. Such properties are of great importance for functionalization reactions for possible applications of reactive polymers. This book deals with the synthesis and design of various functional polymers, the modification of preformed polymer backbones and their various applications.
This groundbreaking single-authored textbook equips students with everything they need to know to truly understand the hugely topical field of biomaterials science, including essential background on the clinical necessity of biomaterials, relevant concepts in biology and materials science, comprehensive and up-to-date coverage of all existing clinical and experimental biomaterials, and the fundamental principles of biocompatibility. It features extensive case studies interweaved with theory, from a wide range of clinical disciplines, equipping students with a practical understanding of the phenomena and mechanisms of biomaterials performance; a whole chapter dedicated to the biomaterials industry itself, including guidance on regulations, standards and guidelines, litigation, and ethical issues to prepare students for industry; informative glossaries of key terms, engaging end-of-chapter exercises, and up-to-date lists of recommended reading. Drawing on the author's 40 years' experience in biomaterials, this is an indispensible resource for students studying these lifesaving technological advances.
Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors,...
Microfluidics-Aided Technologies: Platforms for Next Generation Biological Applications aims to provide comprehensive information of microfluidic technologies, their development and biomedical applications. The book provides the fundamentals of microfluidics and addresses the advances and challenges of microfluidic platforms for diagnostics, biological assays, cellular analysis, and drug delivery. Sections introduce micro-scale flow enabled systems, followed by discussions on applications in diagnostics, prognostics, and cellular analysis in the second and third section. The fourth section focuses on breakthroughs in microfluidics like 3D bioprinting, tissue-on-chip, organ-on-chip, and organ...
Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug ...
Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of d...
Nanotechnology Applications for the Diagnosis and Therapeutic Treatment of Fungal Diseases offers comprehensive coverage of the fundamentals of fungal diseases and the applications of nanotechnology for their diagnosis and treatment. The book discusses the basics of human fungal pathogens and molecular basis of infection, antifungal drugs and their mechanism of action, application of nanoparticles in the delivery of antifungal agents and their roles in nanotechnology-based products for treatment of the fungal diseases, application of nanoparticles for the delivery of antifungal agents and their role in the treatment of various fungal diseases. It also explores various nanotechnology-based pr...