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Due to the rapid increase of digitalization, numerous technologies like the Internet of Medical Things (IoMT), Wearable devices, a huge amount of healthcare data is being generated in multiple formats than ever before. Big data analytics ascertain the proof that has a huge mandate for knowledge discovery, solving problems, computing efficiency. It mainly emphasizes the peculiar tests regarding the information, data processing, analytical modeling, and managing the officialdoms to turn big data into big insight. The main theme of this special issue is to gather the contemporary exploration of the cutting-edge developments, issues, and challenges in big data analytics for smart healthcare syst...
A common feature of cancer metabolism is the ability to obtain essential nutrients from a nutrient-poor environment and use them to maintain viability as well as generate new biomass. Alterations in intracellular and extracellular metabolites can be accompanied by tumor-associated metabolic reprogramming with profound effects on gene expression, cell differentiation, and tumor microenvironment. In these cases, the metabolic microenvironment of the tumor itself can present an immunosuppressive environment that needs to be overcome. Specifically, it will help maximize the efficacy of cancer therapies by identifying targets that suppress or alter cancer metabolism to improve the tumor microenvironment nutrient availability or that modulate immune metabolism to bolster inflammation.
Traditional foods such as red meat and beer have unique, recognizable and desirable sensory traits. However, public awareness about health and the climate crisis is now driving consumers and governmental organizations to consume less meat and alcohol. These recognizable flavors are either missing in novel foods because the material is different (plant-based) or removed after the fermentation process. Therefore, there is a need for innovation of the flavor, texture and trigeminal sensations to meet the expectations for the expanding consumer groups. Improvements with proteins and microbial fermentation processes are currently in the process of making novel foods a global commercial success. F...
In past twenty years or so, information technology has influenced and changed every aspect of our lives and our cultures. Without various IT-based applications, we would find it difficult to keep information stored securely, to process information and business efficiently, and to communicate information conveniently. In the future world, ITs and information engineering will play a very important role in convergence of computing, communication, business and all other computational sciences and application and it also will influence the future world's various areas, including science, engineering, industry, business, law, politics, culture and medicine. The International Conference on Informat...
In recent years, the increase in knowledge about the functioning of the immune system has revealed not only its importance in the defense against external agents such as pathogens or toxins, but also in the control of tumor cells and the importance of the processes of inflammation or immunological tolerance. On the one hand, all this knowledge has allowed a better understanding of the putative pathogenic consequences of immune system dysfunction, which includes inflammatory, autoimmune and immunosuppressive diseases, among others. On the other hand, current knowledge about immunoregulation has paved the way to better prevent or control transplantation rejection. However, such mechanisms unde...
Selected, peer reviewed papers from the 3rd international Conference on Manufacturing Science and Engineering (ICMSE 2012), March 27-29, 2012, Xiamen, China
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This dissertation seeks to understand the driving forces behind fiscal reforms in China in the 1980s and 1990s as well as the specific conditions that shaped reform outcomes. It integrates policy process (including but not limited to elite politics), institution building, and policy substance in three major fiscal reforms: the replacement of profit by tax reform of 1983-1985, the fiscal contract system of 1988, and the tax-sharing system of 1994.