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Autoimmunity was, is and will be considered a hot topic in scientific research. One strong argument that maintains a high research interest in autoimmunity is represented by its dual facets: genetic and environmental. There are rapid advances in identification of various molecular players, from genes to autoantibodies, imposing the immune dysregulation that can lead to the development of diverse immune system diseases. Moreover, numerous endogenous or environmental triggers, such as chronic inflammation, medications, metabolites, viruses, bacteria, pollen, etc. are involved in the development of autoimmunity. The complexity of autoimmunity continues to amaze us, and each new discovery in thi...
Learning from Disease in Pets: A ‘One Health’ Model for Discovery is the first encompassing reference guide for veterinarians, researchers and physicians on conducting studies using spontaneous models of disease in animals. The study of naturally occurring disease in (pet) animals can help model our understanding of the biology, prevention and therapy of human and animal diseases. Studies of pet dogs, for instance, can aid treatment of complex medical problems such as cancer, orthopedic, cardiopulmonary, and neuro-inflammatory diseases, and zoonotic infections. Each chapter within this novel cross-species approach is contributed by a leader, or leaders, in their field of research. Using ...
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