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GH Excess and Deficiency from Fetus to Older Age
Several congenital and acquired conditions, originating from the hypothalamus and pituitary, or in other organs/systems with secondary systemic dissemination, can alter GH secretion leading to transient or chronic somatotroph deficiency or excess. The evolution of radiological, histological, and molecular techniques has profoundly changed the classification as well as treatment indications and types. Management is often challenging because of the heterogeneous and insidious presentation, the multi-organ involvement, and the variable outcome, so that patients should be referred to Pituitary Centers of Excellence. This volume addresses still open issues related to the diagnosis and treatment of GH deficiency and excess, in particular challenging physiologic and pathologic circumstances, and presents the new frontiers of diagnosis – including the application of artificial intelligence – and therapy towards precision, patient-tailored approach, aimed at maximizing treatment effectiveness, tolerability and patient adherence, and consequently, the employment of socio-sanitary resources.
Improving aneurysmal Subarachnoid hemorrhage management, what’s new?
Aneurysmal subarachnoid hemorrhage (aSAH) still represents a significant cause of morbidity and mortality around the world and its outcome can be dramatically impacted by early and expert care. SAH treatment comprises early neurosurgical or endovascular treatment of the ruptured aneurysm, strategies to reduce further neurological injury, and managing systemic complications. In fact, management of aSAH is a multidisciplinary issue and the current state of knowledge is in rapid evolution. Nevertheless, the guidelines are not up to date. The last American aSAH guidelines were issued in 2012 and covered literature up until May 2010, and in 2013 members of the Guidelines Committee of the European...
The Singer's Repertoire, Part IV
Now in paperback! A timeless classic. Includes 8,200 songs in 818 lists for nine voice classifications; indexed by composer, title, vocal range, and publisher. The complete work represents the living song repertoire of today drawn from recital programs, recordings, broadcasts, telecasts, and other sources, and is comprised of Part I: Coloratura, Lyric and Dramatic Soprano, Part II: Mezzo Soprano and Contralto, Part III: Lyric and Dramatic Tenor, and Part IV: Baritone and Bass.
Converging Clinical and Engineering Research on Neurorehabilitation III
The book reports on advanced topics in the areas of neurorehabilitation research and practice. It focuses on new methods for interfacing the human nervous system with electronic and mechatronic systems to restore or compensate impaired neural functions. Importantly, the book merges different perspectives, such as the clinical, neurophysiological, and bioengineering ones, to promote, feed and encourage collaborations between clinicians, neuroscientists and engineers. Based on the 2018 International Conference on Neurorehabilitation (ICNR 2018) held on October 16-20, 2018, in Pisa, Italy,, this book covers various aspects of neurorehabilitation research and practice, including new insights int...
