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The control-theoretic notion of controllability captures the ability to guide a system toward a desired state with a suitable choice of inputs. Controllability of complex networks such as traffic networks, gene regulatory networks, power grids etc. can for instance enable efficient operation or entirely new applicative possibilities. However, when control theory is applied to complex networks like these, several challenges arise. This thesis considers some of them, in particular we investigate how a given network can be rendered controllable at a minimum cost by placement of control inputs or by growing the network with additional edges between its nodes. As cost function we take either the ...
This handbook incorporates new developments in automation. It also presents a widespread and well-structured conglomeration of new emerging application areas, such as medical systems and health, transportation, security and maintenance, service, construction and retail as well as production or logistics. The handbook is not only an ideal resource for automation experts but also for people new to this expanding field.
'A gripping new drama in science ... if you want to understand how the concept of life is changing, read this' Professor Andrew Briggs, University of Oxford When Darwin set out to explain the origin of species, he made no attempt to answer the deeper question: what is life? For generations, scientists have struggled to make sense of this fundamental question. Life really does look like magic: even a humble bacterium accomplishes things so dazzling that no human engineer can match it. And yet, huge advances in molecular biology over the past few decades have served only to deepen the mystery. So can life be explained by known physics and chemistry, or do we need something fundamentally new? I...
This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress...
This book analyzes resilience and sustainability in 7 complex adaptive systems, highlighting transitions from complexity to transdisciplinarity for knowledge integration. It explores second order cybernetics, entropy and reflexivity, contributing to debates on traditional ontological and epistemological positions amid global transformations.
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