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Bioprospecting of Microorganism-Based Industrial Molecules
Discover a comprehensive and current overview of microbial bioprospecting written by leading voices in the field In Bioprospecting of Microorganism-Based Industrial Molecules, distinguished researchers and authors Sudhir P. Singh and Santosh Kumar Upadhyay deliver global perspectives of bioprospecting of biodiversity. The book covers diverse aspects of bioprospecting of microorganisms demonstrating biomass value of nutraceutical, pharmaceutical, biomedical, and bioenergetic importance. The authors present an amalgamation of translational research on bioresource utilization and ecological sustainability that will further the reader’s knowledge of the applications of different microbial dive...
Molecular Evolution of the Major Histocompatibility Complex
From molecules to populations and back In biology, the most vigorous organisms often ensue from a union of two disparate, pure lines. In science, too, laws of hybrid vigor seem to operate at the interface between two disciplines, an interface that often proves to be fertile ground for germinating concepts and new outlooks. The fringes of research into the major histocompatibility complex (Mhc) have provided such an interface several times in the past and the encounters have invigorated fields such as transplantation biology, cellular immunology, and immunogenetics. In the last few years, a new interface has been emerging between Mhc and evolutionary genetics, and particularly the branch of e...
Recent Advances in γδ T Cell Biology: New Ligands, New Functions, and New Translational Perspectives
Gamma/delta (γδ) T-cells are a small subset of T-lymphocytes in the peripheral circulation but constitute a major T-cell population at other anatomical localizations such as the epithelial tissues. In contrast to conventional α/β T-cells, the available number of germline genes coding for T-cell receptor (TCR) variable elements of γδ T-cells is very small. Moreover, there is a prefential localization of γδ T-cells expressing given Vgamma and Vdelta genes in certain tissues. In humans, γδ T-cells expressing the Vg9Vd2-encoded TCR account for anywhere between 50 and >95% of peripheral blood γδ T-cells, whereas cells expressing non-Vd2 genes dominate in mucosal tissues. In mice, ther...
Thüringer Pfarrerbuch
Der 4. Band des Thüringer Pfarrerbuchs verzeichnet die Pfarrer der reußischen Herrschaften von der Reformation bis zum Jahre 1918. Er enthält außer den Lebensdaten und Dienstorten auch die Angaben zu den Karrierestationen und den Familienverhältnissen der aufgenommenen Pfarrer. Eine Einleitung stellt im Überblick die komplizierte Geschichte der reußischen Territorien dar.
Immunoinformatics
Encompasses key developments in immunoinformatics, including immunological databases, sequence analysis, structure modelling, mathematical modelling of the immune system, simulation of laboratory experiments, statistical support for immunilogical experimentation and immuogenomics.
Decoding the Genomic Control of Immune Reactions
This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections. The assembled genome sequences now provide important opportunities for solving these problems, but a major bottleneck is the identification of key sequences and circuits controlling the relevant immune reactions. This will require innovative, interdisciplinary and collaborative strategies of a scale and complexity we are only now beginning to comprehend. Specific problems addressed include the following: What kinds of information are we lacking to understand how the g...
Genome Research
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Biotechnology and the Conservation of Genetic Diversity
The conservation of many endangered species will depend on active management plans for both wild animals and those bred in captivity. A crucial factor is the maintenance of genetic variation in given populations to ensure that inbreeding effects are kept to a minimum. This volume describes the rapid advances that have been made in reproductive biology and molecular genetics, explaining the role and practice of reproductive technology in the breeding of rare and endangered animals in captivity. Calling on both theory and example, the authors highlight three major categories of biotechnology: techniques for managing reproduction (such as in vitro fertilization), techniques for cryopreservation of reproductive material and embryos (the `frozen zoo'), and techniques for genetic analysis. Both practical and ethical issues in captive breeding are explored here by scientists who are leading workers in the field. The work is certain to be a valued resource for zoologists and conservation biologists concerned with issues of diversity and preservation.
