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Preventing Weaponization of CNS-acting Chemicals
Recent advances in neuroscience – the study of the mechanisms within the brain that underlie our behaviours and what happens when these go wrong – have been profound. However, benignly intended neurological research that seeks to understand dysfunction in the central nervous system (CNS) could be misused, for example in the development of novel CNS-acting chemical agent weapons for use in armed conflict and also in repression of civilian populations. This book follows a 3-step Holistic Arms Control approach: examining the (bio)chemical agents and relevant physiological systems they affect, as well as associated dual-use technologies that need to be regulated; analysing a range of potenti...
Toxin and Bioregulator Weapons
This book explores how revolutionary developments and convergence of the chemical, life and associated sciences are impacting contemporary toxin and bioregulator research, and examines the risks of such research being misused for malign purposes. Investigating illustrative cases of dual use research of potential concern in China, India, Iran, Russia, Syria and the USA, the authors discuss how states can ensure such research and related activities are not utilised in weapons development. Although toxins and bioregulators are, in theory, covered by both the Biological and Toxin Weapons Convention and Chemical Weapons Convention, this apparent overlap in reality masks a dangerous regulatory gap – with neither Convention implemented effectively to address threats of weaponisation. This book highlights the potentially damaging consequences for international peace and security, and proposes realistic routes for action by states and the scientific community.
Fluorine Chemistry at the Millennium
This volume brings together contributions by leading researchers covering a wide scope so characteristic of fluorine chemistry. It is a monograph of historical character comprising personalized accounts of progress and events in areas of particular interest.There is also much to interest and instruct chemists from other disciplines as a good proportion of the chapters contain a considerable amount of 'hard' referenced information relating to modern organic, organoelemental and inorganic chemistry. Historians of chemistry and technology will no doubt be tempted to dip into this book, and surely whoever addresses the task of commemorating Moissan's achievement at the 150-years stage will bless us all in some measure for its existence.
Search Based Software Engineering
This book constitutes the refereed proceedings of the 9th International Symposium on Search-Based Software Engineering, SSBSE 2017, held in Paderborn, Germany, in September 2017. The 7 full papers and 5 short papers presented together with 4 challenge track and 2 students student track papers were carefully reviewed and selected from 26 submissions. SSBSE welcomes not only applications from throughout the software engineering lifecycle but also a broad range of search methods ranging from exact Operational Research techniques to nature-inspired algorithms and simulated annealing.
Toxic
Nerve agents are the world's deadliest means of chemical warfare. Nazi Germany developed the first military-grade nerve agents and massive industry for their manufacture - yet, strangely, the Third Reich never used them. At the end of the Second World War, the Allies were stunned to discover this advanced and extensive programme. The Soviets and Western powers embarked on a new arms race, amassing huge chemical arsenals. From their Nazi invention to the 2018 Novichok attack in Britain, Dan Kaszeta uncovers nerve agents' gradual spread across the world, despite international arms control efforts. They've been deployed in the Iran-Iraq War, by terrorists in Japan, in the Syrian Civil War, and by assassins in Malaysia and Salisbury - always with bitter consequences. Toxic recounts the grisly history of these weapons of mass destruction: a deadly suite of invisible, odourless killers.
Comprehensive Organic Functional Group Transformations II
Comprehensive Organic Functional Group Transformations II (COFGT-II) will provide the first point of entry to the literature for all scientists interested in chemical transformations. Presenting the vast subject of organic synthesis in terms of the introduction and interconversion of all known functional groups, COFGT-II provides a unique information source documenting all methods of efficiently performing a particular transformation. Organised by the functional group formed, COFGT-II consists of 144 specialist reviews, written by leading scientists who evaluate and summarise the methods available for each functional group transformation. Also available online via ScienceDirect – featuring...
Comprehensive Medicinal Chemistry II
The first edition of Comprehensive Medicinal Chemistry was published in 1990 and was very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organis...
